CAJ | 학술논문

目的探讨荧光素钠引导在脑胶质瘤切除中的应用.方法对10例脑胶质瘤患者术中应用荧光素钠将肿瘤染色,根据荧光染色强度判定肿瘤的边界并切除.结果星形细胞瘤( WHOⅡ级)4例,间变性星形细胞瘤(WHOⅢ级)、胶质母细胞瘤(WHOⅣ级)各3例,术中肿瘤切除范围与病理学检查相符,术后1周MRI增强扫描显示肿瘤全切除8例,次全切除2例.术后语言肢体运动障碍一过性加重3例,给予对症治疗后逐渐恢复.结论该方法应用简便、安全、经济,对高级别胶质瘤术中可直观、实时判断肿瘤的边界,大大提高了肿瘤切除率.
목적 탐토형광소납인도재뇌효질류절제중적응용.방법 대10례뇌효질류환자술중응용형광소납장종류염색,근거형광염색강도판정종류적변계병절제.결과 성형세포류( WHOⅡ급)4례,간변성성형세포류(WHOⅢ급)、효질모세포류(WHOⅣ급)각3례,술중종류절제범위여병이학검사상부,술후1주MRI증강소묘현시종류전절제8례,차전절제2례.술후어언지체운동장애일과성가중3례,급여대증치료후축점회복.결론 해방법응용간편、안전、경제,대고급별효질류술중가직관、실시판단종류적변계,대대제고료종류절제솔.
Objective To investigate the effects of fluorescence guiding removal in glioma surgery.Methods Ten gliomas were removed assisted by fluorescence guiding.The gliomas were stained with fluorescein sodium and presented yellow color.Based on the intensity of fluorescence,the gliomas were dissected strictly along the boundary between the glioma and normal brain tissues.Results The pathological examination showed that 4 cases were astrocytoma (WHO grade two ),6 anaplastic astrocytomas and glioblastomas.The extent of glioma 's removal was consistent with histo - pathological examination.Postoperatively,enhanced MRI showed that the tumors were radically removed in 8 cases and subtotal in 2.KPS evaluation showed that seven patients improved significantly,three remained or complicated temporarily with movement or lingual disturbance,but they all recovered gradually after treatment.Conclusions Fluorescence- guided glioma removal is a simple,safe and economic method,which will make neurosurgeons find easily the boundary between the higher grade gliomas and the normal tissues.It contributes to the removal effects of glioms.