CAJ | 학술논문

随着新辅助化疗在乳腺癌临床治疗中的广泛应用,新辅助化疗已成为乳腺癌综合治疗的重要组成部分.对于新辅助化疗疗效评价一直缺乏较为及时、准确、有效的方法,常规的体格检查已不能满足临床疗效评价的需要.不断发展的影像学技术在乳腺癌新辅助化疗疗效评价中起重要作用.但只能检测肿瘤形态学改变,存在一定局限性.乳腺血氧功能检测是新近发展的一项新技术,在评估化疗疗效方面有其独到之处,肿瘤生物学标志物因其肿瘤的特异性,在评价新辅助化疗疗效中也越来越重要.本文综述各种方法在乳腺癌新辅助化疗疗效评价中的原理及应用现状.
수착신보조화료재유선암림상치료중적엄범응용,신보조화료이성위유선암종합치료적중요조성부분.대우신보조화료료효평개일직결핍교위급시、준학、유효적방법,상규적체격검사이불능만족림상료효평개적수요.불단발전적영상학기술재유선암신보조화료료효평개중기중요작용.단지능검측종류형태학개변,존재일정국한성.유선혈양공능검측시신근발전적일항신기술,재평고화료료효방면유기독도지처,종류생물학표지물인기종류적특이성,재평개신보조화료료효중야월래월중요.본문종술각충방법재유선암신보조화료료효평개중적원리급응용현상.
With the widespread clinical application of neoadjuvant chemotherapy, it has become an essential part of combination therapy for patients with breast cancer. However, a rapid, accurate, and effective approach for assessing the therapeutic efficacy of neoadjuvant chemotherapy is unavailable. Routine physical examinations cannot provide effective clinical evaluation. Although imaging techniques play an important role in evaluating the therapeutic effect of neoadjuvant chemotherapy, this is limited because it only detects morphologic changes. Blood oxygen detection for breast diseases is an emerging diagnostic technique that has distinctive merit in assessing the efficacy of chemotherapy. Biologic markers are becoming more important in assessing the effect of neoadjuvant chemotherapy for patients with breast cancer. This review summarizes the principles and the current applied practice of these approaches to evaluate the effect of neoadjuvant chemotherapy for patients with breast cancer.