CAJ | 학술논문

目的总结胰腺实性假乳头状瘤的临床特征和手术疗效.方法回顾性分析安徽医科大学附属省立医院2000年1月-2011年2月经病理证实的18例胰腺实性假乳头状瘤患者的临床资料.结果患者发病年龄15 ～46岁,平均27.8岁；其中男性3例,女性15例.肿瘤直径为4.0～15.0 cm,平均7.1 cm；11例肿瘤(61.1％)有界限清楚的囊,5例(27.8％)侵及胰腺外组织；9例(50.0％)含有囊性成分,3例(16.7％)有钙化.静脉侵犯、淋巴侵犯、神经侵犯的频率分别为16.7％(3/18)、0、0.未见淋巴结侵犯和肝转移.胰体尾+脾切除术5例,保脾胰体尾切除术3例,胰十二指肠切除术1例,中段胰腺切除术1例,单纯肿瘤切除术8例.18例患者中15例进行了随访,平均随访47.5个月,所有患者存活未见复发或转移.结论胰腺实性假乳头状瘤好发于年轻女性,经手术治疗(包括单纯肿瘤切除术)的胰腺实性假乳头状瘤患者有良好的疗效.
목적 총결이선실성가유두상류적림상특정화수술료효.방법 회고성분석안휘의과대학부속성립의원2000년1월-2011년2월경병리증실적18례이선실성가유두상류환자적림상자료.결과 환자발병년령15 ～46세,평균27.8세；기중남성3례,녀성15례.종류직경위4.0～15.0 cm,평균7.1 cm；11례종류(61.1％)유계한청초적낭,5례(27.8％)침급이선외조직；9례(50.0％)함유낭성성분,3례(16.7％)유개화.정맥침범、림파침범、신경침범적빈솔분별위16.7％(3/18)、0、0.미견림파결침범화간전이.이체미+비절제술5례,보비이체미절제술3례,이십이지장절제술1례,중단이선절제술1례,단순종류절제술8례.18례환자중15례진행료수방,평균수방47.5개월,소유환자존활미견복발혹전이.결론 이선실성가유두상류호발우년경녀성,경수술치료(포괄단순종류절제술)적이선실성가유두상류환자유량호적료효.
Objective To summarize the clinical features and surgical outcomes in solid pseudopapillary tumor of pancreas.Methods A retrospective clinical analysis was made on 18 cases of solid pseudopapillary tumor of pancreas confirmed by pathological diagnosis from Jan.2000 to Feb.2011.Results The median age of these cases was 27.8 years,ranging from 15 to 46 years.Fifteen cases were female and 3 cases were male.The size of the tumor ranged from 4.0 cm to 15.0 cm,with an average size of 7.1 cm.Eleven of 18 tumors(61.1％ ) had a well-defined capsule,and 5 tumors (27.8％ ) extended beyond the pancreas.Nine of the 18 tumors (50.0％) had a cystic component,and calcification was observed in 3 tumors ( 16.7％ ).The frequency of microscopic venous invasion,lymphatic invasion,and nerve invasion was 16％ (3 of 18),0 and 0 respectively.No lymph node involvement or liver metastasis was observed.Distal pancreatectomy plus splenectomy was done in 5 patients,spleen- preserving distal pancreatectomy in 3,medial pancreatectomy in 1,subtotal stomach- preserving pancreatoduodenectomy in 1,enucleation in 9.Fifteen patients were still alive without recurrent disease or metastasis after a median follow-up of 48 months.Conclusions These results demonstrated that solid pseudopapillary tumor of pancreas occurs mainly in young women,patients with solid pseudopapillary tumor of the pancreas had a favorable outcome after surgical treatment,including enucleation.