中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2008年
7期
47-48
,共2页
王刚平%苏兆花%任雅丽%王洪远
王剛平%囌兆花%任雅麗%王洪遠
왕강평%소조화%임아려%왕홍원
子宫内膜间质肉瘤%临床,病理%免疫组织化学%预后
子宮內膜間質肉瘤%臨床,病理%免疫組織化學%預後
자궁내막간질육류%림상,병리%면역조직화학%예후
Endometrial stromal sarcoma%Clinical,Pathology%Immunohistochemistry%Prognosis
目的 探讨子宫内膜间质肉瘤(ESS)多成分分化与临床生物学特性的关系.方法 运用组织病理学、免疫组织化学及Masson特染分析24例低度恶性子宫内膜间质肉瘤(LGESS)和12例未分化子宫内膜肉瘤(UES)的临床病理资料.结果 LGESS、UES两组中性索分化分别为37.5%(9/24)、83.3%(10/12),差异有统计学意义(P＜0.05);两组平滑肌分化均为33.3%,纤维分化为29.2%、33.3%,上皮样分化为12.5%、16.7%,无统计学意义.结论 ESS可伴多成分分化,主要为性索、平滑肌和纤维分化;预后可能与性索成分有关,而与其他成分无关.
目的 探討子宮內膜間質肉瘤(ESS)多成分分化與臨床生物學特性的關繫.方法 運用組織病理學、免疫組織化學及Masson特染分析24例低度噁性子宮內膜間質肉瘤(LGESS)和12例未分化子宮內膜肉瘤(UES)的臨床病理資料.結果 LGESS、UES兩組中性索分化分彆為37.5%(9/24)、83.3%(10/12),差異有統計學意義(P＜0.05);兩組平滑肌分化均為33.3%,纖維分化為29.2%、33.3%,上皮樣分化為12.5%、16.7%,無統計學意義.結論 ESS可伴多成分分化,主要為性索、平滑肌和纖維分化;預後可能與性索成分有關,而與其他成分無關.
목적 탐토자궁내막간질육류(ESS)다성분분화여림상생물학특성적관계.방법 운용조직병이학、면역조직화학급Masson특염분석24례저도악성자궁내막간질육류(LGESS)화12례미분화자궁내막육류(UES)적림상병리자료.결과 LGESS、UES량조중성색분화분별위37.5%(9/24)、83.3%(10/12),차이유통계학의의(P＜0.05);량조평활기분화균위33.3%,섬유분화위29.2%、33.3%,상피양분화위12.5%、16.7%,무통계학의의.결론 ESS가반다성분분화,주요위성색、평활기화섬유분화;예후가능여성색성분유관,이여기타성분무관.
Objective To study the relationship between clinical-biological significance and multi-differentiation in Endometrial Stromal Sarcomas(ESS).Methods 24 cases of low grade ESSs(LGESS)and 12cases of undifferentiated Endometrial sarcomas(UES)were studied by histopathology immunohi8tochemical method,histochemical method,and clinical follow-up.Results Among the 24 ca8es of LGESSs,there were 9 cases with sex-cord difierentiation,8 cases with smooth muscle differentiation,7 cases with fibrous differentiation,and 3 cases with epithelial differentiation.Among the 12 cases of UESs,there were 10 cases with sex-cord differentiation,4 cases with smooth muscle differenfiation,4 cases with fibrous differentiation,and 2 cases with epitllelial differentiation.There was positive correlmion of sex-cord differentiation between LGESS and UES(P＜0.05).Conclusion ESS can display multi-differentiation.Sex-coed,fibrous and smooth muscle differentiation,the most common types.There might be correlation between prognosis and the amount of sex-cord component and no definite correlation of other multi-differentiation components.
