CAJ | 학술논문

目的探讨PET/CT对头颈部肿瘤放射治疗计划的作用.方法 16例头颈部肿瘤患者行PET/CT和定位CT检查,根据检查结果对16例患者进行TNM分期,比较其分期结果.将定位CT图像传入三维治疗计划系统(TPS),在定位CT图像上勾画大体肿瘤体积(GTV),即CT-GTV;参考PET/CT融合图像在定位CT图像上勾画PET/CT-GTV,比较PET/CT-GTV和CT-GTV.采用Stata 7.0软件分析数据,t检验用于比较PET/CT-GTV和CT-GTV.结果 PET/CT使7例患者TNM分期发生改变.PET/CT-GTV和CT-GTV中位值分别为84.3(46～364)cm3和116.2(58～472)cm3,差异有统计学意义(t=-4.3186, P=0.0005).结论 PET/CT能提高头颈部肿瘤分期和肿瘤靶区定位的准确性.
목적 탐토PET/CT대두경부종류방사치료계화적작용.방법 16례두경부종류환자행PET/CT화정위CT검사,근거검사결과대16례환자진행TNM분기,비교기분기결과.장정위CT도상전입삼유치료계화계통(TPS),재정위CT도상상구화대체종류체적(GTV),즉CT-GTV;삼고PET/CT융합도상재정위CT도상상구화PET/CT-GTV,비교PET/CT-GTV화CT-GTV.채용Stata 7.0연건분석수거,t검험용우비교PET/CT-GTV화CT-GTV.결과 PET/CT사7례환자TNM분기발생개변.PET/CT-GTV화CT-GTV중위치분별위84.3(46～364)cm3화116.2(58～472)cm3,차이유통계학의의(t=-4.3186, P=0.0005).결론 PET/CT능제고두경부종류분기화종류파구정위적준학성.
Objective The aim of this study was to investigate the value of PET/CT in radiation treatment planning of head and neck cancer. Methods Sixteen patients with head and neck cancer underwent PET/CT and enhanced CT imaging. TNM stage was analyzed based on PET/CT and CT. Gross tumor volume (GTV) of PET/CT (PET/CT-GTV) and CT (CT-GTV) were analyzed. Stata 7.0 was used for data analysis, PET/CT-GTV and CT-GTV were compared with t test. Results Based on PET/CT, changes in TNM stage occurred in 7 patients. The median PET/CT-GTV and CT-GTV were 84.3(46～364)cm3 and 116.2(58～472)cm3, respectively, which had a statistically significant difference (t=-4.3186, P=0.0005). Conclusion PET/CT can increase the accuracy of staging and defining the field and target volumes for radiation therapy of head and neck cancer.