CAJ | 학술논문

目的探讨儿童甲型H1N1流感患者发生呼吸衰竭(acute respiratory failure,ARF)的危险因素,为针对性预防其发生提供临床依据.方法对2009年9月至2010年1月我院住院51例甲型H1N1流感儿童的资料进行回顾性分析.结果 51例儿童甲型H1N1流感患儿,5例发生呼吸衰竭,发生率为9.80%,多元回归分析最近有呼吸道感染或使用免疫抑制剂、中性粒细胞计数＞70%,具有统计学意义(P＜0.05),均为独立的危险因素.结论甲型H1N1流感儿童必须预防或积极治疗其合并的细菌感染,以防呼吸衰竭的发生.
목적 탐토인동갑형H1N1류감환자발생호흡쇠갈(acute respiratory failure,ARF)적위험인소,위침대성예방기발생제공림상의거.방법 대2009년9월지2010년1월아원주원51례갑형H1N1류감인동적자료진행회고성분석.결과 51례인동갑형H1N1류감환인,5례발생호흡쇠갈,발생솔위9.80%,다원회귀분석최근유호흡도감염혹사용면역억제제、중성립세포계수＞70%,구유통계학의의(P＜0.05),균위독립적위험인소.결론 갑형H1N1류감인동필수예방혹적겁치료기합병적세균감염,이방호흡쇠갈적발생.
Objective To evaluate high risk factors contribute to acute respiratory failure ( ARF )in children with novel influenza A ( H1N1 ) virus infection. Methods 51 children( ≤ 14 years old ) with novel influenza A ( H1N1 ) virus infection were enrolled from 2009-9-19 to 2010-1-31. To collect the clinical data and restrospective analysis was used in this study. Results 5 cases complated with respiratory failure. The incidence of respiratory failure in children with novel influenza A ( H1N1 ) virus infection in our hospital is 9.80%. Throught Logistic regression analysis, there are high risk factors insreasing children with novel influenza A ( H1N1 ) virus infection liability to respiratory failure: recent respiratory tract infection or use of immunosuppressive agents; neutrophil cell count ＞ 70%. Conclusions In children with novel influenza A ( H1N1 ) virus infection, respiratory tract infection should be prevented and treated actively in order to prevent respiratory failure.