商丘师范学院学报
商丘師範學院學報
상구사범학원학보
JOURNAL OF SHANGQIU TEACHERS COLLEGE
2011年
9期
71-73
,共3页
头孢呋辛钠%茜素红%荷移反应%分光光度法
頭孢呋辛鈉%茜素紅%荷移反應%分光光度法
두포부신납%천소홍%하이반응%분광광도법
cefuroxime sodium%alizarin red%charge-transfer reaction%spectrophotometry
采用紫外可见分光光度法研究了π电子受体茜素红与电子给予体头孢呋辛钠的荷移反应.实验表明,在水溶液中,中性条件下头孢呋辛钠与茜素红在室温下即可形成稳定的络合物,最大吸收波长λmax=520 nm,表观摩尔吸收系数为1.13×104 L·mol-1·cm-1.头孢呋辛钠药物浓度在7.52×10-6～6.66×10-4 mol·L-1范围内服从比尔定律,线性回归方程为A=0.204c（×10-4 mol·L-1）＋0.222,r=0.9992,相对标准偏差为1.2﹪.方法快速、简便、灵敏、准确.
採用紫外可見分光光度法研究瞭π電子受體茜素紅與電子給予體頭孢呋辛鈉的荷移反應.實驗錶明,在水溶液中,中性條件下頭孢呋辛鈉與茜素紅在室溫下即可形成穩定的絡閤物,最大吸收波長λmax=520 nm,錶觀摩爾吸收繫數為1.13×104 L·mol-1·cm-1.頭孢呋辛鈉藥物濃度在7.52×10-6～6.66×10-4 mol·L-1範圍內服從比爾定律,線性迴歸方程為A=0.204c（×10-4 mol·L-1）＋0.222,r=0.9992,相對標準偏差為1.2﹪.方法快速、簡便、靈敏、準確.
채용자외가견분광광도법연구료π전자수체천소홍여전자급여체두포부신납적하이반응.실험표명,재수용액중,중성조건하두포부신납여천소홍재실온하즉가형성은정적락합물,최대흡수파장λmax=520 nm,표관마이흡수계수위1.13×104 L·mol-1·cm-1.두포부신납약물농도재7.52×10-6～6.66×10-4 mol·L-1범위내복종비이정률,선성회귀방정위A=0.204c（×10-4 mol·L-1）＋0.222,r=0.9992,상대표준편차위1.2﹪.방법쾌속、간편、령민、준학.
The charge-transfer reaction between alizarin red as an π-electron acceptors and cefuroxime sodium as an electron donors has been studied by UV-Vis spectrophotometry.The results indicated that the stable complex can be quickly formed based on the charge-transfer reaction between cefuroxime sodium with alizarin red in neutral aqueous solution at room temperature.The complex has strong absorbance at 520 nm.The molar absorptivity of the complex is 1.13×104L·mol-1·cm-1 and the linear range is 7.52×10-6~6.66×10-4 mol·L-1.The linear equation is A=0.204c（×10-4mol·L-1）＋0.222.r=0.9992.RSD is1.2%（n=8）.This method is simple,rapid,accurate and sensitive.
