CAJ | 학술논문

目的探讨轮状病毒、人类杯状病毒引起的感染性腹泻婴幼儿心肌酶及心电图的变化.方法选择卢龙县医院2006年10月-2008年3月收治的256例感染性腹泻住院患儿的粪便标本和空腹血清,检测轮状病毒、人类杯状病毒和心肌酶活性,并检查心电图.结果轮状病毒和人类杯状病毒导致的腹泻患儿谷氨酸氨基转移酶、乳酸脱氢酶、磷酸肌酸激酶和肌酸激酶同工酶的水平间差异无统计学意义(P＜0.05),但均明显高于病毒检测阴性的腹泻患儿(P＜0.05).心肌酶水平增高患儿中部分心电图可有变化,极少发生心律失常和心功能不全.结论轮状病毒和人类杯状病毒感染引起的婴幼儿腹泻,可引发不同程度的心肌损害,两种病毒对心肌酶的影响无明显差异;这种病理变化是否为导致婴幼儿死亡的一种因素,需进一步探讨.
목적 탐토륜상병독、인류배상병독인기적감염성복사영유인심기매급심전도적변화.방법 선택로룡현의원2006년10월-2008년3월수치적256례감염성복사주원환인적분편표본화공복혈청,검측륜상병독、인류배상병독화심기매활성,병검사심전도.결과 륜상병독화인류배상병독도치적복사환인곡안산안기전이매、유산탈경매、린산기산격매화기산격매동공매적수평간차이무통계학의의(P＜0.05),단균명현고우병독검측음성적복사환인(P＜0.05).심기매수평증고환인중부분심전도가유변화,겁소발생심률실상화심공능불전.결론 륜상병독화인류배상병독감염인기적영유인복사,가인발불동정도적심기손해,량충병독대심기매적영향무명현차이;저충병리변화시부위도치영유인사망적일충인소,수진일보탐토.
Objective To explore the changes of myocardial ferment and electrocardiography (ECG) in infants with infectious diarrhea (ID) caused by rotavirus,human-calicivirus.Methods Stool specimens and fasting serum were collected from 256 ID infants admitted to our hospital from October 2006 to March 2008 to detect rotavirus,human-calicivirus and myocardial enzyme activity,and ECG was conducted.Results Myocardial enzymatic rotaviruses caused by rotavirus and human caliciviruses were obviously higher in ID infants than in infants with negative diarrnea (P＜0.05).ECG changed in some of the infants with increased myodiacardial enzyme,rarely with arrhythmia and cardiac insufficiency.Conclusion Infantile diarrhea caused by rotavirus and human-calicivirus may lead to varying degrees of myocardial injuries.There is not significant difference in effects on myocardial enzyme between 2 viruses.Further studies are needed on whether this pathological change is a factor leading to mortality of infants and children.