临床医学工程
臨床醫學工程
림상의학공정
CLINICAL MEDICAL ENGINEERING
2009年
7期
102-104
,共3页
紫菀%紫菀酮%均匀设计%正交设计
紫菀%紫菀酮%均勻設計%正交設計
자완%자완동%균균설계%정교설계
Aster tataricus L. f.%shionone%uniform design%orthogunal test
目的 优选回流法提取紫菀中有效成分紫菀酮的工艺条件.方法 以紫菀酮的含量为指标,通过选用U8(8×8×4×2)均匀设计试验,L9(3φ)正交设计试验和单因素平行试验,对提取工艺的溶剂种类、溶剂用量、提取次数和提取时间4个因素进行优选研究,以筛选出紫菀酮的最佳提取工艺条件.结果 优选得到的最佳提取工艺条件是用24倍量95%乙醇回流提取1次,每次1小时,紫菀酮的转移率达到90%以上.结论 优化的条件经试验验证和中试生产,表明工艺条件稳定可行,可用于工业大生产.
目的 優選迴流法提取紫菀中有效成分紫菀酮的工藝條件.方法 以紫菀酮的含量為指標,通過選用U8(8×8×4×2)均勻設計試驗,L9(3φ)正交設計試驗和單因素平行試驗,對提取工藝的溶劑種類、溶劑用量、提取次數和提取時間4箇因素進行優選研究,以篩選齣紫菀酮的最佳提取工藝條件.結果 優選得到的最佳提取工藝條件是用24倍量95%乙醇迴流提取1次,每次1小時,紫菀酮的轉移率達到90%以上.結論 優化的條件經試驗驗證和中試生產,錶明工藝條件穩定可行,可用于工業大生產.
목적 우선회류법제취자완중유효성분자완동적공예조건.방법 이자완동적함량위지표,통과선용U8(8×8×4×2)균균설계시험,L9(3φ)정교설계시험화단인소평행시험,대제취공예적용제충류、용제용량、제취차수화제취시간4개인소진행우선연구,이사선출자완동적최가제취공예조건.결과 우선득도적최가제취공예조건시용24배량95%을순회류제취1차,매차1소시,자완동적전이솔체도90%이상.결론 우화적조건경시험험증화중시생산,표명공예조건은정가행,가용우공업대생산.
Objective In order to optimize the reflux extracting technology ofshionone from Aster tataricus L. F. Method Using shionone determined by HPLC as the content index, the effects of alcohol concentration, solvent amount, extraction time and extraction times on extra, on technology were evaluated by uniform design, orthogonal design and single factor design. Results The optimum extraction condition obtained was 95% ethanol. 24 folds of the materials weight, and reflux for 1 time, 1 hour. Conclusion The optimized process is proved to be efficient and stable by validated and magnified test, and it is suitable for industrialized extraction ofshionone from Aster tataricus L. F.
