CAJ | 학술논문

从青岛地区糖尿病(DM)和高尿酸血症流行病学调查数据库中,排除既往已诊断糖尿病者,对资料完整者3125例,按照不同糖代谢状态、BMI、高血压(HT)和TG水平分组,比较血尿酸(SUA)水平的变化.调整年龄、BMI和TG后,新诊断DM的SUA水平明显低于正常糖耐量组(NGT)和糖调节受损组(IGR)(P均＜0.05),其中在男性,NGT组的SUA水平最高(390±3μmol/L),而在女性IGR组SUA水平(328±5μmol/L)明显高于NGT和新诊断DM组(P均＜0.05);BMI＞27.8 kg/m2亚组的SUA水平为最高(P＜0.01);高血压组和高TG组的SUA水平均分别高于正常血压和正常TG组(P分别为＜0.05和＜0.01).随着NGT、IGT到新诊断DM糖代谢异常的加重SUA水平下降,可能是机体抗氧化反应减弱的一种表现,而在高血压组的SUA升高可作为血管并发症的预测指标.
종청도지구당뇨병(DM)화고뇨산혈증류행병학조사수거고중,배제기왕이진단당뇨병자,대자료완정자3125례,안조불동당대사상태、BMI、고혈압(HT)화TG수평분조,비교혈뇨산(SUA)수평적변화.조정년령、BMI화TG후,신진단DM적SUA수평명현저우정상당내량조(NGT)화당조절수손조(IGR)(P균＜0.05),기중재남성,NGT조적SUA수평최고(390±3μmol/L),이재녀성IGR조SUA수평(328±5μmol/L)명현고우NGT화신진단DM조(P균＜0.05);BMI＞27.8 kg/m2아조적SUA수평위최고(P＜0.01);고혈압조화고TG조적SUA수평균분별고우정상혈압화정상TG조(P분별위＜0.05화＜0.01).수착NGT、IGT도신진단DM당대사이상적가중SUA수평하강,가능시궤체항양화반응감약적일충표현,이재고혈압조적SUA승고가작위혈관병발증적예측지표.
The study of NGT(n=1913), IGR(n=636) and DM (n=576) patients showed that: 1. The lowest SUA levels were found in newly diagnosed DM, after adjusting age, body mass index and triglyceride.especially in diabetes women. SUA levels were most elevated in men with NGT and women with IGR (both P<0.05).2.Obese men and women with BMI of 27.8 kg/m2 had highest mean SUA levels in all categories of diabetes status (P<0.01).3.Hypertension and high triglyceride subjects had higher SUA levels than normotensive and normal triglyceride persons regardless of their diabetes status respectively, after adjusting age and body mass index.