CAJ | 학술논문

目的:了解天然植物无花果的药用研究进展,以期总结该植物的主要药用价值,指导临床应用.资料来源:检索Medline 1950-01/2004-09与无花果药用相关的文章,检索词"ficus carica",并限定文章语言种类为English.检索国家知识基础设施全文数据库CNKI 1999-01/2004-09与无花果药用相关的文章,限定文章语言种类为中文,检索词"无花果".资料选择:对资料进行初审,选取关于无花果的药用价值研究的文献,筛除与药用价值研究无关的研究,对剩余的文献开始查找全文.纳入标准为①无花果药用价值的实验研究.②研究包括无花果、叶、汁及其各种提取物或制剂.排除标准:重复性研究.资料提炼:共收集到226篇关于无花果药用价值的研究文章,30个研究符合纳入标准.排除的196篇文章,189篇为临床经验报道或重复性研究,7篇为综述类文章.资料综合:相关实验研究表明,无花果、叶、汁及其各种提取物或制剂有着广泛的药用价值,发现了其多种药理作用,如抗肿瘤、调节机体代谢如调整血糖、血脂、胆固醇等,可提高机体抗氧化能力,抗菌、抗病毒、调节免疫,以及调节凝血、拮抗肿瘤放、化学药物治疗中的毒副反应的作用等;其致敏的案例国内外亦见少量报道.结论:作为药物,无花果具有广泛的药理作用及临床应用价值.对其药用价值的研究多集中在抗肿瘤及调节代谢两方面,且其各种活性成分的分离、提纯及其之间的复合作用以及药理、毒理作用研究尚不明确.随着对其研究的不断深入,其新的药理作用也必将发现.
목적:료해천연식물무화과적약용연구진전,이기총결해식물적주요약용개치,지도림상응용.자료래원:검색Medline 1950-01/2004-09여무화과약용상관적문장,검색사"ficus carica",병한정문장어언충류위English.검색국가지식기출설시전문수거고CNKI 1999-01/2004-09여무화과약용상관적문장,한정문장어언충류위중문,검색사"무화과".자료선택:대자료진행초심,선취관우무화과적약용개치연구적문헌,사제여약용개치연구무관적연구,대잉여적문헌개시사조전문.납입표준위①무화과약용개치적실험연구.②연구포괄무화과、협、즙급기각충제취물혹제제.배제표준:중복성연구.자료제련:공수집도226편관우무화과약용개치적연구문장,30개연구부합납입표준.배제적196편문장,189편위림상경험보도혹중복성연구,7편위종술류문장.자료종합:상관실험연구표명,무화과、협、즙급기각충제취물혹제제유착엄범적약용개치,발현료기다충약리작용,여항종류、조절궤체대사여조정혈당、혈지、담고순등,가제고궤체항양화능력,항균、항병독、조절면역,이급조절응혈、길항종류방、화학약물치료중적독부반응적작용등;기치민적안례국내외역견소량보도.결론:작위약물,무화과구유엄범적약리작용급림상응용개치.대기약용개치적연구다집중재항종류급조절대사량방면,차기각충활성성분적분리、제순급기지간적복합작용이급약리、독리작용연구상불명학.수착대기연구적불단심입,기신적약리작용야필장발현.
BACKGROUND: To review progressions in the pharmacological study of natural plant Ficus carica L. (fig), summarize its main pharmacological effects so as to manifest values in clinical practice.DATA SOURCES: .By computer retrieval system, the relevant papers on the researches on Ficus carica were retrieved on Medline from January 1950 to September 2004 and limited at the referred word "Ficus carica" in English. Simultaneously, the relevant papers were searched by the computer on China National Knowledge Infrastructure (CNKI) database from January 1999 to September 2004, focusing on the referred word "Fieus carica" in Chinese.STUDY SELECTION: Of all the relevant papers, ones focusing on the pharmacological study of Ficus carica were selected and the whole text were checked, meanwhile those had no relation with the pharmacological latex as well as various constituents and preparations. Exclusion criterion:repeated studies.DATA EXTRACTION: A total of 226 papers were checked on the study of Ficus carica, 30 papers were consistent with the standards. Among the 196 excluded papers, 189 were excluded because they were clinical experience report or repeated studies, 7 were reviews.DATA SYNTHESIS: Investigations of the fig, its leaves and latex as well as various constituents and preparations, have revealed many pharmacological effects such as: anti-tumor effects, the ability to mediate body metabolism, mediating hyperglycemia, hyperlipidemia and cholesterol levels, enhancing oxidation resistance, antibiotic effects, antivirus effects, the ability to mediate immunity, activating blood coagulation etc. It also may play an important role in supportive therapy in tumor treatment by reducing toxicity and side effects in actinotheraphy and chemotherapy. Several reports of anaphylaxis after fig intake have reported both in China and abroad.CONCLUSION: As an herb, fig has wide pharmacological effects and clinical practise values. The main pharmacological studies of it were focused on its anti-tumor effects and the ability to mediate body metabolism.Separation and purification of its active components and determining the interactions between them as well as the pharmacological and toxicological effects need further study. New pharmacological effect s will be found by studying various fig extracts.