CAJ | 학술논문

目的探讨芭蕉根不同极性溶剂提取物的抗炎、镇痛活性.方法采用二甲苯致小鼠耳肿胀实验、角叉菜胶致小鼠足肿胀和小鼠棉球肉芽肿等实验进行抗炎实验,采用醋酸扭体法进行镇痛实验,对芭蕉根的石油醚提取物、正丁醇提取物,80%乙醇提取物和水提取物进行抗炎和镇痛实验研究.结果芭蕉根石油醚和正丁醇提取物可以明显的减轻二甲苯所致的小鼠耳廓肿胀和棉球肉芽肿的重量,对角叉菜胶所致的小鼠足肿胀也有明显的抑制作用;芭蕉根乙醇提取物和水提取物对醋酸所致小鼠扭体反应有较好的抑制作用.结论在相同剂量下,芭蕉根石油醚提取物和正丁醇提取物显示出较好的抗炎活性,而80%乙醇和水提取物相对具有较好的镇痛活性.
목적 탐토파초근불동겁성용제제취물적항염、진통활성.방법 채용이갑분치소서이종창실험、각차채효치소서족종창화소서면구육아종등실험진행항염실험,채용작산뉴체법진행진통실험,대파초근적석유미제취물、정정순제취물,80%을순제취물화수제취물진행항염화진통실험연구.결과 파초근석유미화정정순제취물가이명현적감경이갑분소치적소서이곽종창화면구육아종적중량,대각차채효소치적소서족종창야유명현적억제작용;파초근을순제취물화수제취물대작산소치소서뉴체반응유교호적억제작용.결론 재상동제량하,파초근석유미제취물화정정순제취물현시출교호적항염활성,이80%을순화수제취물상대구유교호적진통활성.
Objective To evaluate the anti-inflammatory and analgesic effects of different extracts from Musa basjoo.Methods Samples were extracted from Musa basjoo with ethyl acetate,n-butyl alcohol,80% alcohol or water.Anti-inflammatory effect of Musa basjoo were observed by mouse abdominal cavity capillary permeability increase test induced by acetic acid,mouse auricle swelling test induced by xylene,mouse pedal swelling test induced by carrageenin and cotton granuloma test in mice.Analgesic action of Musa basjoo was observed by mouse aceticacid-induced twisting test.Results In the same dose,both of the sample of ethyl acetate and n-butyl alcohol could reduce pedal swelling,aurical swelling and cotton granuloma of mice.Both of the sample of 80% alcohol and water sample could inhibit twisting response of mice obviously.Conclusion Both of the sample of ethyl acetate and n-butyl alcohol have anti-inflammatory action,while both of the sample of 80% alcohol and water have analgesic effect.