CAJ | 학술논문

背景:镍铬合金烤瓷牙是广泛应用于临床的修复体,对其安全性的争论通常限于口腔及邻近组织器官,而与全身范围内疾病如肾中毒的关联性尚未被重视.目的:分析镍铬合金烤瓷牙导致肾病的可能性及长期应用临床的安全性.方法:以"镍铬合金,烤瓷牙,肾中毒"为中文检索词,以"nickle chromium alloy,porcelain crown,nephridium toxicosis"为英文检索词,采用计算机检索1989-01/2009-10维普中文科技期刊数据库、中国CNKI学术总库、万方数据库、中国生物医学文献数据库、Biosis Previews数据库及BioOne生物全文期刊数据库相关文献.纳入与镍铬合金烤瓷牙及金属离子毒性相关研究,排除重复研究.结果与结论:通过查阅国内外文献,文章从镍铬合金的腐蚀性及其在口腔和全身范围的蓄积和影响,镍铬烤瓷合金在体内所释放金属元素及其衍生物的直接毒性和肾中毒的易感性,以及镍铬离子造成肾脏损害的可能途径几方面分析了镍铬合金烤瓷牙的重金属离子腐蚀、扩散以及导致肾中毒的可能性,为进一步研究镍铬合金烤瓷牙的安全性提供依据.
배경:얼락합금고자아시엄범응용우림상적수복체,대기안전성적쟁론통상한우구강급린근조직기관,이여전신범위내질병여신중독적관련성상미피중시.목적:분석얼락합금고자아도치신병적가능성급장기응용림상적안전성.방법:이"얼락합금,고자아,신중독"위중문검색사,이"nickle chromium alloy,porcelain crown,nephridium toxicosis"위영문검색사,채용계산궤검색1989-01/2009-10유보중문과기기간수거고、중국CNKI학술총고、만방수거고、중국생물의학문헌수거고、Biosis Previews수거고급BioOne생물전문기간수거고상관문헌.납입여얼락합금고자아급금속리자독성상관연구,배제중복연구.결과여결론:통과사열국내외문헌,문장종얼락합금적부식성급기재구강화전신범위적축적화영향,얼락고자합금재체내소석방금속원소급기연생물적직접독성화신중독적역감성,이급얼락리자조성신장손해적가능도경궤방면분석료얼락합금고자아적중금속리자부식、확산이급도치신중독적가능성,위진일보연구얼락합금고자아적안전성제공의거.
BACKGROUND: Dental porcelain crown containing Ni-Cr alloy has been widely used in modern dentistry. The dispute of its safety is limited in oral cavity and neighbor tissues, however, the relevance between Ni-Cr alloy and systemic disease, such as nephridium toxicosis, are poorly understood. OBJECTIVE: To analyze the possibility of Ni-Cr porcelain crown resulted nephropathy and to explore its long-term clinical safety.METHODS: Databases of VIP, CNKI, Wanfang, CBMdisc, Biosis Previews and BioOne were researched by computer with key words of "nickle chromium alloy, porcelain crown, nephridium toxicosis" both in Chinese and English. Literatures concerning Ni-Cr porcelain crown and toxicity of related metal ion were included, repetitive research was excluded. RESULTS AND CONCLUSION: By consulting literatures, the possibility of erosion and release of heavy metal ion lead to nephridium toxicosis were analyzed with following aspects: effects of Ni-Cr alloy corrosivity and its accumulation on oral cavity or systemic disease; direct toxicity of released metal ions from Ni-Cr alloy and susceptivity of nephridium toxicosis; and the possible ways for renal damage resulted by Ni-Cr ion. This study can provide a basis for the further research concerning security of dental porcelain crown containing Ni-Cr alloy.