中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
7期
792-793
,共2页
王天松%冯旭霞%姚震%罗江宾%陈良%张云波%陈其敬%马瑞莲%秦喜竹
王天鬆%馮旭霞%姚震%囉江賓%陳良%張雲波%陳其敬%馬瑞蓮%秦喜竹
왕천송%풍욱하%요진%라강빈%진량%장운파%진기경%마서련%진희죽
急性冠状动脉综合征%血管成形术,气囊,冠状动脉%血栓抽吸术
急性冠狀動脈綜閤徵%血管成形術,氣囊,冠狀動脈%血栓抽吸術
급성관상동맥종합정%혈관성형술,기낭,관상동맥%혈전추흡술
Acute coronary syndrome%Angioplasty,balloon,coronary%Thrombus aspiration
目的 评价血栓抽吸术对高危非ST段抬高型急性冠状动脉综合征(NSTEACS)患者介入疗效的影响.方法 78例行急诊经皮冠状动脉介入治疗( PCI)的高危NSTEACS患者按随机数字表法分为研究组和对照组,各39例.研究组先行冠状动脉内血栓抽吸术,再行PCI;对照组直接行PCI.观察术后心肌灌注分级、血清心肌肌钙蛋白T(cTnT)和术后1个月左心室射血分数(LVEF)的差异.结果 研究组与对照组相比,心肌灌注率0/1级为7.7％(3/39)比28.2％ (11/39) (P ＜0.05);2级为23.1％ (9/39)比30.8％(12/39) (P ＞0.05);3级为69.2％ (27/39)比41.0％ (16/39) (P ＜0.05).研究组和对照组血清cTnT分别为(4.7±1.3) μg/L和(9.3±3.1)μg/L,研究组低于对照组(P＜0.05);LVEF分别为(55±15)％和(40±10)％,研究组高于对照组(P＜0.05).结论 高危NSTEACS患者行早期PCI前进行血栓抽吸术可改善心肌灌注,减少心肌坏死,改善术后心脏功能.
目的 評價血栓抽吸術對高危非ST段抬高型急性冠狀動脈綜閤徵(NSTEACS)患者介入療效的影響.方法 78例行急診經皮冠狀動脈介入治療( PCI)的高危NSTEACS患者按隨機數字錶法分為研究組和對照組,各39例.研究組先行冠狀動脈內血栓抽吸術,再行PCI;對照組直接行PCI.觀察術後心肌灌註分級、血清心肌肌鈣蛋白T(cTnT)和術後1箇月左心室射血分數(LVEF)的差異.結果 研究組與對照組相比,心肌灌註率0/1級為7.7％(3/39)比28.2％ (11/39) (P ＜0.05);2級為23.1％ (9/39)比30.8％(12/39) (P ＞0.05);3級為69.2％ (27/39)比41.0％ (16/39) (P ＜0.05).研究組和對照組血清cTnT分彆為(4.7±1.3) μg/L和(9.3±3.1)μg/L,研究組低于對照組(P＜0.05);LVEF分彆為(55±15)％和(40±10)％,研究組高于對照組(P＜0.05).結論 高危NSTEACS患者行早期PCI前進行血栓抽吸術可改善心肌灌註,減少心肌壞死,改善術後心髒功能.
목적 평개혈전추흡술대고위비ST단태고형급성관상동맥종합정(NSTEACS)환자개입료효적영향.방법 78례행급진경피관상동맥개입치료( PCI)적고위NSTEACS환자안수궤수자표법분위연구조화대조조,각39례.연구조선행관상동맥내혈전추흡술,재행PCI;대조조직접행PCI.관찰술후심기관주분급、혈청심기기개단백T(cTnT)화술후1개월좌심실사혈분수(LVEF)적차이.결과 연구조여대조조상비,심기관주솔0/1급위7.7％(3/39)비28.2％ (11/39) (P ＜0.05);2급위23.1％ (9/39)비30.8％(12/39) (P ＞0.05);3급위69.2％ (27/39)비41.0％ (16/39) (P ＜0.05).연구조화대조조혈청cTnT분별위(4.7±1.3) μg/L화(9.3±3.1)μg/L,연구조저우대조조(P＜0.05);LVEF분별위(55±15)％화(40±10)％,연구조고우대조조(P＜0.05).결론 고위NSTEACS환자행조기PCI전진행혈전추흡술가개선심기관주,감소심기배사,개선술후심장공능.
Objective To assess the effects of thrombus aspiration during percutaneous coronary intervention(PCI) on high risk non-ST element acute coronary syndrome(NSTEACS).Methods A total of 78 patients with NSTEACS were randomly assigned to the thrombus-aspiration group and the conventional PCI group.In the thrombus-aspimtion group,patients had thrombus-aspiration before urgent PCI;in the eonventional PCI group,patients underwent urgent PCI routinely.The endpoints included angiographic evidence of myocardial perfusion(myocardial blush grade),the peak volume of cardiac troponin T(cTnT) and left ventrieular ejection fraction(LVEF)one month later.Results In the thrombus-aspiration group and the conventional-PCI group,patients with blush grades 0/1 were 7.7 ％(3/39) vs 28.2％(11/39),P ＜ 0.05,grades 2 were 23.1％(9/39) vs 30.8％(12/39,P ＞ 0.05) and grades 3 were 69.2 ％(27/39) vs 41.0％(16/39),P ＜ 0.05.The peak volume of cTnT [(4.7±1.3) μg/L vs(9.3±3.1) μg/L,P ＜ 0.05 ] and LVEF one month later [(55±15) ％ vs(40±10) ％(P ＜0.05) ] between the thrombus-aspiration group and the conventional PCI group were observed.Conclusion Thrombus aspiration during urgent PCI in patients with high risk NSTEACS shows an optimistic effect on myocardial perfusion,myocardial necrosis and heart function.
