中国医药
中國醫藥
중국의약
CHINA MEDICINE
2011年
8期
930-932
,共3页
张明华%张华%王素莉%王麒%刘冀琴%高红薇%汤庆林%刘瑜%周欣%庞博
張明華%張華%王素莉%王麒%劉冀琴%高紅薇%湯慶林%劉瑜%週訢%龐博
장명화%장화%왕소리%왕기%류기금%고홍미%탕경림%류유%주흔%방박
2型糖尿病%红细胞体积分布宽度%颈动脉内中膜厚度
2型糖尿病%紅細胞體積分佈寬度%頸動脈內中膜厚度
2형당뇨병%홍세포체적분포관도%경동맥내중막후도
Type 2 diabetes mellitus%Red cell volume distribution width%Intima media thickness
目的 评估红细胞体积分布宽度(RDW)与2型糖尿病(T2DM)患者颈动脉内中膜厚度(IMT)的关系.方法 将225例T2DM患者按照IMT是否正常进行分为2组,IMT正常组45例,ITM升高组180例,比较2组患者实验室检测指标,进行Logistic回归分析,并将RDW与IMT进行相关分析.结果 IMT升高组较IMT正常组患者年龄更大[(62.2±9.5)岁比(53.9±9.6)岁],患高血压者比例更高[61.7%(111/180)比31.1%(14/45)],血肌酐更高[(65.3±30.8)μmol/L比(52.4±15.7)μmol/L],且RDW值更高[(13.3±0.9)%vs(12.7±0.6)%],上述4个因素的差异均具有统计学意义(均P＜0.01).Logistic回归显示,RDW是IMT升高的危险因素之一(OR=2.272,95% CI 1.241～4.195,P=0.008).RDW与IMT存在显著相关性(r=0.280,P=0.000).结论 RDW与T2DM患者IMT存在密切的相关性,可能对于T2DM患者的预后判断有一定用价值.
目的 評估紅細胞體積分佈寬度(RDW)與2型糖尿病(T2DM)患者頸動脈內中膜厚度(IMT)的關繫.方法 將225例T2DM患者按照IMT是否正常進行分為2組,IMT正常組45例,ITM升高組180例,比較2組患者實驗室檢測指標,進行Logistic迴歸分析,併將RDW與IMT進行相關分析.結果 IMT升高組較IMT正常組患者年齡更大[(62.2±9.5)歲比(53.9±9.6)歲],患高血壓者比例更高[61.7%(111/180)比31.1%(14/45)],血肌酐更高[(65.3±30.8)μmol/L比(52.4±15.7)μmol/L],且RDW值更高[(13.3±0.9)%vs(12.7±0.6)%],上述4箇因素的差異均具有統計學意義(均P＜0.01).Logistic迴歸顯示,RDW是IMT升高的危險因素之一(OR=2.272,95% CI 1.241～4.195,P=0.008).RDW與IMT存在顯著相關性(r=0.280,P=0.000).結論 RDW與T2DM患者IMT存在密切的相關性,可能對于T2DM患者的預後判斷有一定用價值.
목적 평고홍세포체적분포관도(RDW)여2형당뇨병(T2DM)환자경동맥내중막후도(IMT)적관계.방법 장225례T2DM환자안조IMT시부정상진행분위2조,IMT정상조45례,ITM승고조180례,비교2조환자실험실검측지표,진행Logistic회귀분석,병장RDW여IMT진행상관분석.결과 IMT승고조교IMT정상조환자년령경대[(62.2±9.5)세비(53.9±9.6)세],환고혈압자비례경고[61.7%(111/180)비31.1%(14/45)],혈기항경고[(65.3±30.8)μmol/L비(52.4±15.7)μmol/L],차RDW치경고[(13.3±0.9)%vs(12.7±0.6)%],상술4개인소적차이균구유통계학의의(균P＜0.01).Logistic회귀현시,RDW시IMT승고적위험인소지일(OR=2.272,95% CI 1.241～4.195,P=0.008).RDW여IMT존재현저상관성(r=0.280,P=0.000).결론 RDW여T2DM환자IMT존재밀절적상관성,가능대우T2DM환자적예후판단유일정용개치.
Objective To evaluate the relationship between red cell volume distribution width(RDW) and intima media thickness(IMT) in type 2 diabetes mellitus(T2DM) patients. Methods Two hundred and twentyfive T2DM patients consecutively admitted into our hospital were divided into two groups according to whether IMT were increased or not. The baseline clinical data of the patients were collected and the relationship between RDW and IMT was evaluated. Results The age of the IMT increased group was higher than that of normal IMT group [(62.2 ± 9. 5) years vs (53. 9 ± 9. 6) years]. The proportion of patients with hypertension was higher[61.7% (111/180) vs 31.1%(14/45)] and serum creatinine was higher[(65.3 ±30.8) μmol/L vs (52.4 ± 15.7)μmol/L]. There were significant differences of age, plasma creatinine, RDW and hypertension history between the two groups (P=0.000, 0.001, 0.000, 0.000 respectively). There was significant correlation between RDW and IMT(r= 0.28, P = 0. 000). Logistic regression analysis indicated that RDW was one of the risk factors of IMT (OR = 2.272, 95% CI 1.241 -4.195, P=0.008). Conclusion RDW may be significantly related to IMT in T2DM patients and may be valuable to the prognosis.
