中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2008年
11期
7-8
,共2页
张豪伟%王卫东%赵亮%王利民
張豪偉%王衛東%趙亮%王利民
장호위%왕위동%조량%왕이민
骨巨细胞瘤%降钙素受体%免疫组织化学
骨巨細胞瘤%降鈣素受體%免疫組織化學
골거세포류%강개소수체%면역조직화학
Giant cell tumor of bone%Calcitonin receptors%Immunohistochemistry
目的 检测降钙素受体(CTR)在骨巨细胞瘤(GCr)组织中的表达,探讨其与骨巨细胞瘤(GCT)Jaffe病理分级及生物学行为的关系.方法 采用S-P免疫组织化学方法对12例经过Jaffe病理分级的骨巨细胞瘤标本进行检测,并用10例骨软骨瘤标本作对照.结果 降钙素受体在骨巨细胞瘤中的阳性率为91.7%,骨软骨瘤中的阳性率为20%,两组比较差异有统计学意义(P<0.01).结论 降钙素受体在骨巨细胞瘤中高度表达,但Jaffe病理分级与免疫组化表达不完全一致.
目的 檢測降鈣素受體(CTR)在骨巨細胞瘤(GCr)組織中的錶達,探討其與骨巨細胞瘤(GCT)Jaffe病理分級及生物學行為的關繫.方法 採用S-P免疫組織化學方法對12例經過Jaffe病理分級的骨巨細胞瘤標本進行檢測,併用10例骨軟骨瘤標本作對照.結果 降鈣素受體在骨巨細胞瘤中的暘性率為91.7%,骨軟骨瘤中的暘性率為20%,兩組比較差異有統計學意義(P<0.01).結論 降鈣素受體在骨巨細胞瘤中高度錶達,但Jaffe病理分級與免疫組化錶達不完全一緻.
목적 검측강개소수체(CTR)재골거세포류(GCr)조직중적표체,탐토기여골거세포류(GCT)Jaffe병리분급급생물학행위적관계.방법 채용S-P면역조직화학방법대12례경과Jaffe병리분급적골거세포류표본진행검측,병용10례골연골류표본작대조.결과 강개소수체재골거세포류중적양성솔위91.7%,골연골류중적양성솔위20%,량조비교차이유통계학의의(P<0.01).결론 강개소수체재골거세포류중고도표체,단Jaffe병리분급여면역조화표체불완전일치.
Objective To investigate the expression of calcitonin receptors(CTR) in giant cell tumors of bone and osteochondroma detect the correlation between CTR with Jaffe pathological grade and the biological behavior of the tumor. Methods The expression of CTR was detected in the group that included 12 cases of giant cell tumors of bone and in control group that included 10 cases of osteochondromas by using S - P immunohistochemical method. Results The positive rate of CTR in 12 cases of giant cell tumors of bone was 91.7% and 20% in 10 cases of osteochondromas. There was a significant difference between giant cell tumor of bone and osteochondroma (P < 0. 01 ) . Conclusion The expression of CTR in giant cell tumor of bone is prominently and it is not consistent with Jaffe pathological grade.
