湖北农业科学
湖北農業科學
호북농업과학
2010年
3期
635-637,647
,共4页
陈佳娟%李剑勇%杨亚军%李新圃%张继瑜%魏小娟%周旭正
陳佳娟%李劍勇%楊亞軍%李新圃%張繼瑜%魏小娟%週旭正
진가연%리검용%양아군%리신포%장계유%위소연%주욱정
中药注射剂%体外抑茵试验%最小抑菌浓度
中藥註射劑%體外抑茵試驗%最小抑菌濃度
중약주사제%체외억인시험%최소억균농도
Chinese medicine injection%antibacterial action%minimal inhibitory concentration
"炎毒热清"中药注射剂是由连翘、金银花、黄芩等中药混合提取配制而成的复方制剂.为了筛选最佳工艺和配方,采用杯碟法分别对不同提取工艺和配方进行了金黄色葡萄球菌、胸膜肺炎放线杆菌、多杀性巴氏杆菌、大肠杆菌4种细菌的体外抑茼试验.结果表明,"炎毒热清"中药注射剂复方A~复方F对金黄色葡萄球菌、胸膜肺炎放线杆菌、多杀性巴氏杆菌的抑茼作用比复方1~复方6的抑菌作用显著,尤其是复方F的抑菌作用最显著.在复方1~复方6中.复方6的抑茵作用较其他复方显著.全部复方对大肠杆菌效果不明显.通过体外抑菌试验可知,复方F的体外抑菌效果最好,可作为预选方进一步研究.
"炎毒熱清"中藥註射劑是由連翹、金銀花、黃芩等中藥混閤提取配製而成的複方製劑.為瞭篩選最佳工藝和配方,採用杯碟法分彆對不同提取工藝和配方進行瞭金黃色葡萄毬菌、胸膜肺炎放線桿菌、多殺性巴氏桿菌、大腸桿菌4種細菌的體外抑茼試驗.結果錶明,"炎毒熱清"中藥註射劑複方A~複方F對金黃色葡萄毬菌、胸膜肺炎放線桿菌、多殺性巴氏桿菌的抑茼作用比複方1~複方6的抑菌作用顯著,尤其是複方F的抑菌作用最顯著.在複方1~複方6中.複方6的抑茵作用較其他複方顯著.全部複方對大腸桿菌效果不明顯.通過體外抑菌試驗可知,複方F的體外抑菌效果最好,可作為預選方進一步研究.
"염독열청"중약주사제시유련교、금은화、황금등중약혼합제취배제이성적복방제제.위료사선최가공예화배방,채용배설법분별대불동제취공예화배방진행료금황색포도구균、흉막폐염방선간균、다살성파씨간균、대장간균4충세균적체외억동시험.결과표명,"염독열청"중약주사제복방A~복방F대금황색포도구균、흉막폐염방선간균、다살성파씨간균적억동작용비복방1~복방6적억균작용현저,우기시복방F적억균작용최현저.재복방1~복방6중.복방6적억인작용교기타복방현저.전부복방대대장간균효과불명현.통과체외억균시험가지,복방F적체외억균효과최호,가작위예선방진일보연구.
"Yandureqing" was Chinese traditional medicine injection. It was prepared from Weeping forsythia, Honeysuckle flower, Radix scutellariae and other medicines. The experiment was to select the best formula through the test of in vitroantibacterial action. Cup method was used to compare different extract technology and prescription with the antibacterial ac-tion on Staphylococcus aureus, Actinobacillus pleuropneumoniae, Pasteurella multocida, Escherichia. coli. The formula A-formula F had more antibacterial effect on S. aureus, A. pleuropneunwniae, P. multocida than the formula l~formula 6. For-mula F was the most antibacterial in the formula A~ formula F. Formula 6 was the most antibacterial in the formula 1 -formula 6. All formula had no effect on E. coli. Formula F had the best antibacterial effect and needed to further study.