CAJ | 학술논문

目的观察鼻塞持续气道正压通气(NCPAP)治疗新生儿呼吸系统疾病的疗效.方法 67例呼吸系统疾病新生儿采用NCPAP机+常规临床治疗,观察治疗前后血气变化.结果治疗后1h血氧饱和度( SpO2)、氧分层(PaO2)较治疗前明显上升(t=3.84,15.50,均P＜0.05),二氧化碳分压(PaCO2)无明显变化(t=1.96,P＞0.05).持续气道正压(CPAP)治疗成功54例,CPAP治疗失败13例.最终治愈51例,好转11例,放弃治疗4例,死亡1例.结论早期使用NCPAP治疗新生儿呼吸系统疾病疗效显著,可减少机械通气应用,且方法简便易行、无创安全.
목적 관찰비새지속기도정압통기(NCPAP)치료신생인호흡계통질병적료효.방법 67례호흡계통질병신생인채용NCPAP궤+상규림상치료,관찰치료전후혈기변화.결과 치료후1h혈양포화도( SpO2)、양분층(PaO2)교치료전명현상승(t=3.84,15.50,균P＜0.05),이양화탄분압(PaCO2)무명현변화(t=1.96,P＞0.05).지속기도정압(CPAP)치료성공54례,CPAP치료실패13례.최종치유51례,호전11례,방기치료4례,사망1례.결론 조기사용NCPAP치료신생인호흡계통질병료효현저,가감소궤계통기응용,차방법간편역행、무창안전.
Objective To observe the effects of nasal continuous positive airway pressure(NCPAP) on neonatal respiratory disease.Methods 67 newborns with respiratory disease undergone the treatment of NCPAP and routine clinic treatment.The changes of blood gas index and therapeutic effects were observed.The changes of blood gas between the pretherapy and post-treatment were compared.Results The numerus of PaO2,SpO2 was increased apparently at 1 hour after treament with NCPAP.The difference was significant ( t =3.84,15.50,all P ＜ 0.05 ).But the PaCO2 had no apparent change and the difference was not significant(t =1.96,P ＞ 0.05 ).54 newborns were treated successfully and 13 newborns were treated unsuccessfully.51 newborns were cured,11 newborns were improved and 1 patient was dead at Last.Conclusion The early application of NCPAP on neonatal respiratory disease was very effective.It could reduce the use of mechanial ventilation,and it was a convenient,safe and effect-prominent method.