诊断病理学杂志
診斷病理學雜誌
진단병이학잡지
CHINESE JOURNAL OF DIAGNOSTIC PATHOLOGY
2010年
1期
35-38
,共4页
前列腺肉瘤%非霍奇金淋巴瘤%免疫组化
前列腺肉瘤%非霍奇金淋巴瘤%免疫組化
전렬선육류%비곽기금림파류%면역조화
PS%Immunohistochemistry%NHL
目的 探讨前列腺肉瘤(PS)的病理学诊断、组织学分类、鉴别诊断及发病率情况.方法 收集解放军总医院1990-2008年间诊断的PS共19例,做常规HE及免疫组化染色,并复习文献.结果 PS占同期前列腺恶性肿瘤的2.1%.发病年龄17～74岁,平均40.8岁.19例肉瘤中平滑肌肉瘤9例,横纹肌肉瘤6例,非霍奇金淋巴瘤(NHL)2例,恶性间质瘤1例,梭形细胞肉瘤1例.不同类型PS免疫组化染色各具其特征.结论 前列腺肉瘤发病率很低,临床上主要表现为进行性排尿困难.影像学检查有助于发现前列腺占位性病变,确诊要靠前列腺穿刺活检组织学诊断,免疫组化染色有助于PS分类.本病恶性程度高,预后极差.
目的 探討前列腺肉瘤(PS)的病理學診斷、組織學分類、鑒彆診斷及髮病率情況.方法 收集解放軍總醫院1990-2008年間診斷的PS共19例,做常規HE及免疫組化染色,併複習文獻.結果 PS佔同期前列腺噁性腫瘤的2.1%.髮病年齡17～74歲,平均40.8歲.19例肉瘤中平滑肌肉瘤9例,橫紋肌肉瘤6例,非霍奇金淋巴瘤(NHL)2例,噁性間質瘤1例,梭形細胞肉瘤1例.不同類型PS免疫組化染色各具其特徵.結論 前列腺肉瘤髮病率很低,臨床上主要錶現為進行性排尿睏難.影像學檢查有助于髮現前列腺佔位性病變,確診要靠前列腺穿刺活檢組織學診斷,免疫組化染色有助于PS分類.本病噁性程度高,預後極差.
목적 탐토전렬선육류(PS)적병이학진단、조직학분류、감별진단급발병솔정황.방법 수집해방군총의원1990-2008년간진단적PS공19례,주상규HE급면역조화염색,병복습문헌.결과 PS점동기전렬선악성종류적2.1%.발병년령17～74세,평균40.8세.19례육류중평활기육류9례,횡문기육류6례,비곽기금림파류(NHL)2례,악성간질류1례,사형세포육류1례.불동류형PS면역조화염색각구기특정.결론 전렬선육류발병솔흔저,림상상주요표현위진행성배뇨곤난.영상학검사유조우발현전렬선점위성병변,학진요고전렬선천자활검조직학진단,면역조화염색유조우PS분류.본병악성정도고,예후겁차.
Objective To discuss the pathological features, histological classification, differential diagnosis and the incidence of the prostate sarcoma (PS). Methods 19 cases of PS were collected from 1990 to 2008 in this hospital and observed by light microscopy and immunohistochemical technique with literature review. Results The PS was accounted for 2.1% of all the prostatic malignant tumors. The average age was 40.8 years old (ranged from 17 to 74 years). Among of the 19 cases, 9 were leiomyosarcoma, 6 rhabdomyosarcoma, 2 non Hodgkin's lymphoma (NHL), 1 malignant stromal tumor and 1 spindle cell sarcoma. Different PS had its own immunohistochemical features. Conclusions The PS is rare and dysuria always is the first symptoms. Ultrosound, CT and MRI examinations are helpfull to find this tumor. Needle biopsy contributes to a definite diagnosis and the immunohistochemical staining helps for the classification of the disease. This tumor is a high malignancy with very poor prognosis.
