CAJ | 학술논문

目的探讨食管癌术后早期持续肠内营养支持对患者预后的影响.方法将248例食管胃底贲门癌根治手术的患者随机分为肠内营养(EN)组和肠外营养(PN)组各124例,手术后第1天开始分别给予营养支持6 d,于术前1 d、术后8 d检测体质量、血常规、肝功能,并观察并发症的发生率.结果 EN组体质量、红细胞数、血红蛋白、白蛋白等下降幅度少于PN组(P＜0.01).EN组患者术后无吻合口瘘发生,肺部感染发生率为13.8%,胸液量平均为780 ml,无切口愈合不良者;PN组患者吻合口瘘发生率3.2%,肺部感染发生率28.2%,胸液量平均为1 842 ml,切口愈合不良发生率7.2%.结论术后早期EN比PN对食管癌营养状况的改善更好,并发症发生率更低.
목적 탐토식관암술후조기지속장내영양지지대환자예후적영향.방법 장248례식관위저분문암근치수술적환자수궤분위장내영양(EN)조화장외영양(PN)조각124례,수술후제1천개시분별급여영양지지6 d,우술전1 d、술후8 d검측체질량、혈상규、간공능,병관찰병발증적발생솔.결과 EN조체질량、홍세포수、혈홍단백、백단백등하강폭도소우PN조(P＜0.01).EN조환자술후무문합구루발생,폐부감염발생솔위13.8%,흉액량평균위780 ml,무절구유합불량자;PN조환자문합구루발생솔3.2%,폐부감염발생솔28.2%,흉액량평균위1 842 ml,절구유합불량발생솔7.2%.결론 술후조기EN비PN대식관암영양상황적개선경호,병발증발생솔경저.
Objective To investigate the effect of early enteral nutrition.Methods 248 patients with esophageal and gastric carcinoma were randomly divided into two groups,and received enteral nutrition(EN)and parenteral nutrition(PN)each continuously for 6 days after operation.The body weight,blood routine test,liver function,and postoperative day 8 were compared with those before operation.Results The body weight,red blood cell count,and the levels of hemoglobin,serum albumin and transaminase decreased less in EN group than those in PN group(P＜0.01).The complication rates of anastomotic fistula,pulmonary infection,and delayedincision healing and average volume of pleural effusion were 0,13.8%,0,780ml in EN groups,while 3.2%,28.2%,7.2%,1842ml in PN group.Conclusion Early postoperative enteral nutirtion after esophageal carcinoma surgery can improve nutritional status and reduce complications in comparision with parenteral nutrition.