白血病·淋巴瘤
白血病·淋巴瘤
백혈병·림파류
JOURNAL OF LEUKEMIA & LYMPHOMA
2009年
12期
742-743
,共2页
白血病%粒细胞%急性%预后
白血病%粒細胞%急性%預後
백혈병%립세포%급성%예후
Leukemia%myeloeytic%acute%Prognosis
目的 观察初发急性髓系白血病(AML)[非急性早幼粒细胞白血病(APL)]诱导治疗 7-10 d骨髓白血病细胞下降指数 (MBDI) 与预后的关系.方法 回顾性分析109例AML(非API,)患者,比较持续缓解组、复发组、未缓解组初次诱导治疗7-10 d MBDI 的差异;进行该指数与持续缓解率、复发率的相关分析.结果 MBDI 均值持续缓解组为0.8856,显著高于复发组(0.4445) 和未缓解组(0.3903)(P<0.0001);该指数与持续缓解率呈正相关(P<0.01),与复发率呈负相关(P<0.01). 结论初次诱导治疗7-10 d时MBDI对AML(非APL)具有早期判断预后的价值.
目的 觀察初髮急性髓繫白血病(AML)[非急性早幼粒細胞白血病(APL)]誘導治療 7-10 d骨髓白血病細胞下降指數 (MBDI) 與預後的關繫.方法 迴顧性分析109例AML(非API,)患者,比較持續緩解組、複髮組、未緩解組初次誘導治療7-10 d MBDI 的差異;進行該指數與持續緩解率、複髮率的相關分析.結果 MBDI 均值持續緩解組為0.8856,顯著高于複髮組(0.4445) 和未緩解組(0.3903)(P<0.0001);該指數與持續緩解率呈正相關(P<0.01),與複髮率呈負相關(P<0.01). 結論初次誘導治療7-10 d時MBDI對AML(非APL)具有早期判斷預後的價值.
목적 관찰초발급성수계백혈병(AML)[비급성조유립세포백혈병(APL)]유도치료 7-10 d골수백혈병세포하강지수 (MBDI) 여예후적관계.방법 회고성분석109례AML(비API,)환자,비교지속완해조、복발조、미완해조초차유도치료7-10 d MBDI 적차이;진행해지수여지속완해솔、복발솔적상관분석.결과 MBDI 균치지속완해조위0.8856,현저고우복발조(0.4445) 화미완해조(0.3903)(P<0.0001);해지수여지속완해솔정정상관(P<0.01),여복발솔정부상관(P<0.01). 결론초차유도치료7-10 d시MBDI대AML(비APL)구유조기판단예후적개치.
Objective To investigate relationship of the marrow blast decline index(MBDI)in AML (not APL)at the first inductive treatment for 7-10 days and the prognosis.Methods 109 cases of AML were retrospectively analyzed(not APL),to compare theⅡmarrow blast decline index in AML(not APL)at the first inductive treatment for 7-10 days in the continue relieve group,the relapse group and the non-remission group,analyzed the correlation of the MBDI and continue relapse rate,the MBDI and relapse rate.Results The MBDI mean value is 0.8856 in continue relieve group.significantly higher than that of the relapse group (mean=0.4445)and the non-remission group(mean=0.3903)(P<0.0001).The MBDl positively correlated with continue relapse rate(P<0.01);negatively correlated with relapse rate(P<0.01).Conclusion The marrow blast decline index in AML(not APL) at the first inductive treatment for 7-10 days was significant for early assesment ofthe prognosis.
