中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
5期
591-592
,共2页
胸膜炎,结核性%尿激酶%地塞米松%异烟肼
胸膜炎,結覈性%尿激酶%地塞米鬆%異煙肼
흉막염,결핵성%뇨격매%지새미송%이연정
Peritmitis,tuberculous%Urokinase%Dexamethasone%Isoniazid
目的 探讨结核性包裹性胸膜炎的最佳治疗方法.方法 将60例结核性包裹性胸膜炎患者分为观察组和对照组,各30例,观察组在胸腔穿刺抽液后胸腔注入尿激酶10万U、地塞米松10 mg、异烟肼0.3g,对照组胸腔内注入异烟肼0.3g.2组患者的抗结核化疗方案均为2HRE(S) Z/10HRE.疗程1年.每周2次常规胸腔穿刺,比较2组临床疗效.结果 胸腔穿刺次数、胸腔积液消失时间、临床症状消失时间观察组总有效率分别为100.0％ (30/30)、96.7％ (29/30)、100.0％ (30/30)；对照组总有效率分别为60.0％(18/30)、70.0％ (21/30)、50.0％ (15/30).胸膜无粘连增厚观察组22例(73.3％)、对照组10例(33.3％).2组疗效对比,观察组均高于对照组,差异有统计学意义(P＜0.05).结论 胸腔内注入尿激酶、地塞米松、异烟肼能溶解胸腔积液房隔,明显增加下一次胸腔穿刺抽水量,减少抽胸腔积液次数,缩短患者不适症状消失时间,减轻或消除胸膜肥厚粘连的发生.
目的 探討結覈性包裹性胸膜炎的最佳治療方法.方法 將60例結覈性包裹性胸膜炎患者分為觀察組和對照組,各30例,觀察組在胸腔穿刺抽液後胸腔註入尿激酶10萬U、地塞米鬆10 mg、異煙肼0.3g,對照組胸腔內註入異煙肼0.3g.2組患者的抗結覈化療方案均為2HRE(S) Z/10HRE.療程1年.每週2次常規胸腔穿刺,比較2組臨床療效.結果 胸腔穿刺次數、胸腔積液消失時間、臨床癥狀消失時間觀察組總有效率分彆為100.0％ (30/30)、96.7％ (29/30)、100.0％ (30/30)；對照組總有效率分彆為60.0％(18/30)、70.0％ (21/30)、50.0％ (15/30).胸膜無粘連增厚觀察組22例(73.3％)、對照組10例(33.3％).2組療效對比,觀察組均高于對照組,差異有統計學意義(P＜0.05).結論 胸腔內註入尿激酶、地塞米鬆、異煙肼能溶解胸腔積液房隔,明顯增加下一次胸腔穿刺抽水量,減少抽胸腔積液次數,縮短患者不適癥狀消失時間,減輕或消除胸膜肥厚粘連的髮生.
목적 탐토결핵성포과성흉막염적최가치료방법.방법 장60례결핵성포과성흉막염환자분위관찰조화대조조,각30례,관찰조재흉강천자추액후흉강주입뇨격매10만U、지새미송10 mg、이연정0.3g,대조조흉강내주입이연정0.3g.2조환자적항결핵화료방안균위2HRE(S) Z/10HRE.료정1년.매주2차상규흉강천자,비교2조림상료효.결과 흉강천자차수、흉강적액소실시간、림상증상소실시간관찰조총유효솔분별위100.0％ (30/30)、96.7％ (29/30)、100.0％ (30/30)；대조조총유효솔분별위60.0％(18/30)、70.0％ (21/30)、50.0％ (15/30).흉막무점련증후관찰조22례(73.3％)、대조조10례(33.3％).2조료효대비,관찰조균고우대조조,차이유통계학의의(P＜0.05).결론 흉강내주입뇨격매、지새미송、이연정능용해흉강적액방격,명현증가하일차흉강천자추수량,감소추흉강적액차수,축단환자불괄증상소실시간,감경혹소제흉막비후점련적발생.
Objective To investigate the optimal observation of tuberculous encapsulated pleurisy.Methods Sixty patients with tuberculous package pleurisy were divided into the observation group and control group.The observation group was given urokinase 100000 U,dexamethasone 10 mg,isoniazid 0.3 g,and the control group were injected with isoniazid 0.3 g into pleural cavity.Anti-tuberculosis chemotherapy regimens of two groups were 2 HRE (S) Z/10 HRE.After routine pleural puncture twice weekly,clinical curative effects were compared.Results The total effective rate of the times of pleural puncture,disappearance time of pleural effusion and the time of clinical symptoms disappeared in observation group was 100.0％ (30/30),96.7 ％ (29/30),100.0％ (30/30) respectively; in the control group,the total effective rate was 60.0％ (18/30),70.0％ (21/30),50.0％ (15/30) respectively.The patients with no adhesion of pleural thickening was 22 cases (73.3％) in observation group and 10 cases (33.3％) in control group.The curative effect in the observation group were higher than that in the control group(P ＜ 0.05).Conclusion The injection of urokinase,dexamethasone and isoniazid into pleural cavity can dissolve pleural effusion room,significantly increase the volume of pumping water in next pleural cavity puncture,reduce the frequency of pleural effusion,shorten the disappearance time of patients' symptoms and reduce or eliminate the disappearance of pleural hypertrophy adhesion.
