中国医药
中國醫藥
중국의약
CHINA MEDICINE
2009年
4期
286-288
,共3页
季加富%张岩%张成明%王松清%焦万珍
季加富%張巖%張成明%王鬆清%焦萬珍
계가부%장암%장성명%왕송청%초만진
蛛网膜下腔阻滞%氯胺酮%布比卡因%膀胱灌洗%体温
蛛網膜下腔阻滯%氯胺酮%佈比卡因%膀胱灌洗%體溫
주망막하강조체%록알동%포비잡인%방광관세%체온
Subarachnoid block%Ketamine%Bupivicaine%Bladder irrigation%Temperature
目的 观察蛛网膜下腔阻滞和氯胺酮静脉麻醉两种方式对大剂量膀胱灌洗中老年家兔体温的影响.方法 20只免龄30个月龄清洁级雄性家兔完伞随机分为布比卡因组和氯胺酮组各10例.所有家兔给予乳酸林格氏液5 ml/(kg·h)静脉滴注.布比卡因组予0.5%布比卡因1 ml行蛛网膜下腔阻滞;氯胺酬组予氯胺酮10 mg/kg静脉注射维持麻醉.2组家兔均用室温(22～24℃)蒸馏水同等灌洗速度(15 ml/min)膀胱灌洗1 h.记录灌洗前及灌洗后10、20、30、40、50、60 min以及停止灌洗后5、10、15、20、25、30 min的直肠温度.结果 2组灌洗开始后各时间点直肠温度逐渐下降,与灌洗前相比,差异有统计学意义(P<0.01或P<0.05);灌洗期间各时间点布比卡凶组直肠温度低于氯胺酮组,差异有统计学意义(P<0.05);停止灌洗后5 min时2组直肠温度[(32.09±0.40)℃与(35.17±0.43)℃]与灌洗结束时[(32.14±0.27)℃与(35.31±0.59)℃]比较,差异无统计学意义(P>0.05);2组灌洗结束10 min后各时间点直肠温度回升,与灌洗结束时相比差异有统计学意义(P<0.01或P<0.05).[布比卡因组各时间点直肠温度与氯胺酮组比较,差异有统计学意义(P<0.05).结论 灌洗期间布比卡因蛛网膜下腔阻滞较氯胺酮静脉麻醉直肠温度下降得快且幅度大;停止灌洗后直肠温度恢复慢.这说明氯胺酮较有利于体温稳定,是围手术期麻醉方式的较好选择.
目的 觀察蛛網膜下腔阻滯和氯胺酮靜脈痳醉兩種方式對大劑量膀胱灌洗中老年傢兔體溫的影響.方法 20隻免齡30箇月齡清潔級雄性傢兔完傘隨機分為佈比卡因組和氯胺酮組各10例.所有傢兔給予乳痠林格氏液5 ml/(kg·h)靜脈滴註.佈比卡因組予0.5%佈比卡因1 ml行蛛網膜下腔阻滯;氯胺酬組予氯胺酮10 mg/kg靜脈註射維持痳醉.2組傢兔均用室溫(22～24℃)蒸餾水同等灌洗速度(15 ml/min)膀胱灌洗1 h.記錄灌洗前及灌洗後10、20、30、40、50、60 min以及停止灌洗後5、10、15、20、25、30 min的直腸溫度.結果 2組灌洗開始後各時間點直腸溫度逐漸下降,與灌洗前相比,差異有統計學意義(P<0.01或P<0.05);灌洗期間各時間點佈比卡兇組直腸溫度低于氯胺酮組,差異有統計學意義(P<0.05);停止灌洗後5 min時2組直腸溫度[(32.09±0.40)℃與(35.17±0.43)℃]與灌洗結束時[(32.14±0.27)℃與(35.31±0.59)℃]比較,差異無統計學意義(P>0.05);2組灌洗結束10 min後各時間點直腸溫度迴升,與灌洗結束時相比差異有統計學意義(P<0.01或P<0.05).[佈比卡因組各時間點直腸溫度與氯胺酮組比較,差異有統計學意義(P<0.05).結論 灌洗期間佈比卡因蛛網膜下腔阻滯較氯胺酮靜脈痳醉直腸溫度下降得快且幅度大;停止灌洗後直腸溫度恢複慢.這說明氯胺酮較有利于體溫穩定,是圍手術期痳醉方式的較好選擇.
목적 관찰주망막하강조체화록알동정맥마취량충방식대대제량방광관세중노년가토체온적영향.방법 20지면령30개월령청길급웅성가토완산수궤분위포비잡인조화록알동조각10례.소유가토급여유산림격씨액5 ml/(kg·h)정맥적주.포비잡인조여0.5%포비잡인1 ml행주망막하강조체;록알수조여록알동10 mg/kg정맥주사유지마취.2조가토균용실온(22～24℃)증류수동등관세속도(15 ml/min)방광관세1 h.기록관세전급관세후10、20、30、40、50、60 min이급정지관세후5、10、15、20、25、30 min적직장온도.결과 2조관세개시후각시간점직장온도축점하강,여관세전상비,차이유통계학의의(P<0.01혹P<0.05);관세기간각시간점포비잡흉조직장온도저우록알동조,차이유통계학의의(P<0.05);정지관세후5 min시2조직장온도[(32.09±0.40)℃여(35.17±0.43)℃]여관세결속시[(32.14±0.27)℃여(35.31±0.59)℃]비교,차이무통계학의의(P>0.05);2조관세결속10 min후각시간점직장온도회승,여관세결속시상비차이유통계학의의(P<0.01혹P<0.05).[포비잡인조각시간점직장온도여록알동조비교,차이유통계학의의(P<0.05).결론 관세기간포비잡인주망막하강조체교록알동정맥마취직장온도하강득쾌차폭도대;정지관세후직장온도회복만.저설명록알동교유리우체온은정,시위수술기마취방식적교호선택.
Objective To observe the effect of subarachnoid block and Ketamine intravenous anesthesia on temperature of elder rabbits during the bladder irrigatio. Methods Twenty ( 30 months old ) male rabbits were randomly divided into two groups: Bupivicaine group and Ketamine group. All rabbits were given Lactated Ringer's Solution at the rate of 5 ml/( kg · h). Group B was given 0.5% bupivacaine 1 ml;Group K was maintenanced with Ketamine 10 mg· kg-1 by intravenous injection. All rabbits were irrigated with distilled water (room temperature, 22 ℃ ~ 24 ℃ ) for 1 hour at the same rate of 15 mL/min. The rectal temperature was recorded at the time of 10 min before irrigation, 10, 20, 30,40,50, 60 minutes during irrigation and 5, 10, 15,20,25,30 min after irrigation respectively. Results During the irrigation, the temperature in group B significantly dropped at all time points( P>0.01 ), so was group K ( P>0.01 or P>0.05 ) ; Compared with group K, group B showed statistical significanees at all time pionts(P>0.05 ). After the irrigation, the temperature in group B significantly raised at all time points (P>0.01 or P>0.05 ), so was group K ( P>O. 01 ). Compared with group K, group B also showed statistical significances at all time points( P>0.05 ). Conclusion The temperature in group B significantly drops with fast and a large amount of irrigation and slowly recovers after irrigation. Katamine helps stabilize the temperature.
