CAJ | 학술논문

目的:研究针刺治疗更年期综合征的临床疗效及其内分泌机制.方法:47例更年期综合征患者分为针刺组32例(采用主穴肾俞、足三里、三阴交针刺治疗),对照组15例(采用口服谷维素治疗),观察两组治疗前后的Kupperman指数,进行疗效评价.并采用放射免疫分析法检测针刺组25例患者治疗前后血清E2、T、FSH、LH含量变化.结果:针刺治疗能改善更年期综合征患者的临床症状,疗效优于对照组;针刺治疗后患者血清E2含量明显升高,LH、T含量明显降低,FSH虽有下调趋势但无统计学意义.结论:针刺治疗更年期综合征疗效肯定.针刺治疗能够改善更年期综合征患者垂体-性腺轴的功能,该作用可能是其治疗更年期综合征的重要机制.
목적:연구침자치료경년기종합정적림상료효급기내분비궤제.방법:47례경년기종합정환자분위침자조32례(채용주혈신유、족삼리、삼음교침자치료),대조조15례(채용구복곡유소치료),관찰량조치료전후적Kupperman지수,진행료효평개.병채용방사면역분석법검측침자조25례환자치료전후혈청E2、T、FSH、LH함량변화.결과:침자치료능개선경년기종합정환자적림상증상,료효우우대조조;침자치료후환자혈청E2함량명현승고,LH、T함량명현강저,FSH수유하조추세단무통계학의의.결론:침자치료경년기종합정료효긍정.침자치료능구개선경년기종합정환자수체-성선축적공능,해작용가능시기치료경년기종합정적중요궤제.
Objective:To study the clinical effect and the endocrine mechanism of acupuncture therapy on menopause syndrome.Method:There were 47 cases with menopause syndrome,which were divided into two groups,32 cases in the acupuncture group,treated by acupuncture with main acupoins of Shenshu (BL 23),Zusanli (ST 36) and Sanyinjiao (SP 6),and 15 cases in the control group,treated by orally taking the Oryzanol.The Kupperman index of the two groups was observed before and after treatment for evaluating the therapeutic effect.The changes of blood-serum F2,T,FSH,LH of the 25 cases in the acupuncture group were tested by radioimmunoassay before and after the treatment.Results:The acupuncture therapy can relieve the clinical symptoms of menopause syndrome,and its therapeutic effect was better than Oryzanol.After being treated by acupuncture therapy,the content of blood-serum E2 obviously increased,while the contents of LH and T declined,and the FSH also had a tendency to lower,but it was not statistically significant.Conclusion:The therapeutic effect of acupuncture therapy for menopause is confirmed.The acupuncture therapy can improve the function of hypophysial-gonadal axis of the patient with menopause syndrome,which may be the main mechanism of the acupuncture therapy for treating menopause syndrome.