中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2011年
3期
247-249
,共3页
陈昭君%杨喜山%董平栓%李志娟%王可
陳昭君%楊喜山%董平栓%李誌娟%王可
진소군%양희산%동평전%리지연%왕가
冠心病%惊恐障碍%心率变异性%自主神经功能
冠心病%驚恐障礙%心率變異性%自主神經功能
관심병%량공장애%심솔변이성%자주신경공능
Coronary heart disease%Panic disorder%Heart rate variability%Autonomic nervous function
目的 通过监测惊恐障碍、冠心病及其共病时患者的心率变异性(HRV)变化来探讨惊恐障碍对冠心病患者自主神经功能的影响.方法 所有入选者需符合冠心病或(和)惊恐障碍诊断及剔除标准,将入选者分为4组:冠心病组40例,惊恐障碍组36例,冠心病合并惊恐障碍组27例,健康对照组40例,采用24h动态心电图监测系统,观察HRV的时域、频域指标,采用方差分析,使用统计软件进行分析.结果 与正常组相比,冠心病组、惊恐障碍组、冠心病合并惊恐障碍组的HRV各指标均降低,其中冠心病合并惊恐障碍患者HRV降低最明显,其时域指标SDNN、SDANN、PNN50、RMSSD分别为(70.40±14.74)ms、(91.72±24.46)ms、(2.83±2.07)%、(15.66±7.45)ms,频域指标LF、HF为(647.54±129.24)ms2、(596.16±127.66)ms2,与其余3组比较差异有统计学意义(P＜0.05).结论 冠心病、惊恐障碍患者自主神经功能紊乱,冠心病合并惊恐障碍患者自主神经功能紊乱更明显.
目的 通過鑑測驚恐障礙、冠心病及其共病時患者的心率變異性(HRV)變化來探討驚恐障礙對冠心病患者自主神經功能的影響.方法 所有入選者需符閤冠心病或(和)驚恐障礙診斷及剔除標準,將入選者分為4組:冠心病組40例,驚恐障礙組36例,冠心病閤併驚恐障礙組27例,健康對照組40例,採用24h動態心電圖鑑測繫統,觀察HRV的時域、頻域指標,採用方差分析,使用統計軟件進行分析.結果 與正常組相比,冠心病組、驚恐障礙組、冠心病閤併驚恐障礙組的HRV各指標均降低,其中冠心病閤併驚恐障礙患者HRV降低最明顯,其時域指標SDNN、SDANN、PNN50、RMSSD分彆為(70.40±14.74)ms、(91.72±24.46)ms、(2.83±2.07)%、(15.66±7.45)ms,頻域指標LF、HF為(647.54±129.24)ms2、(596.16±127.66)ms2,與其餘3組比較差異有統計學意義(P＜0.05).結論 冠心病、驚恐障礙患者自主神經功能紊亂,冠心病閤併驚恐障礙患者自主神經功能紊亂更明顯.
목적 통과감측량공장애、관심병급기공병시환자적심솔변이성(HRV)변화래탐토량공장애대관심병환자자주신경공능적영향.방법 소유입선자수부합관심병혹(화)량공장애진단급척제표준,장입선자분위4조:관심병조40례,량공장애조36례,관심병합병량공장애조27례,건강대조조40례,채용24h동태심전도감측계통,관찰HRV적시역、빈역지표,채용방차분석,사용통계연건진행분석.결과 여정상조상비,관심병조、량공장애조、관심병합병량공장애조적HRV각지표균강저,기중관심병합병량공장애환자HRV강저최명현,기시역지표SDNN、SDANN、PNN50、RMSSD분별위(70.40±14.74)ms、(91.72±24.46)ms、(2.83±2.07)%、(15.66±7.45)ms,빈역지표LF、HF위(647.54±129.24)ms2、(596.16±127.66)ms2,여기여3조비교차이유통계학의의(P＜0.05).결론 관심병、량공장애환자자주신경공능문란,관심병합병량공장애환자자주신경공능문란경명현.
Objective To investigate the changes of autonomic nerve function of coronary heart disease (CHD) patients with panic disorder(PD). Methods All the subjects who met with the diagnostic code of CHD and PD were divided into CHD group(n=40) ,PD group(n=36) ,comorbid CHD and PD group(n=27) ,and 40physical examinee were recruited as normal control group. They had a 24 hours Holter ECG monitoring by time and frequency domain analysis of heart rate variability. ANOVA analysis was utilized to statistic the collected data. Results Compared with normal controls,the patients of others groups had every indexs of HRV were reduced. The indexs of HRV of comorbid CHD and PD were lower than the patients of CHD or PD group. The score of time domain SDNN(70.40 ± 14.74)ms,SDANN(91.72 ± 24.46)ms,PNN50(2.83 ±2.07)%, RMSSD( 15.66 ±7.45)ms,frequency domain LF(647.54 ± 129.24)ms2, HF(596. 16± 127.66) ms2 in comorbid CHD and PD. There were significant differences with others groups(P ＜ 0.05 ). Conclusion The autonomic nervous functional of the patients with CHD and PD were in disorder. The autonomic nervous functional disorder of the patients with comorbid CHD and PD was more severe.
