CAJ | 학술논문

埃兹(Ezrin)蛋白是埃兹蛋白、根蛋白、膜突蛋白(ezrin-radixin-moesin,ERM)家族重要成员之一,连接于细胞膜与细胞骨架之间,在维持细胞的形状、极性、运动以及信号转导方面发挥着重要作用.近年研究发现,埃兹蛋白在多数肿瘤细胞中异常高表达,在肿瘤癌变、肿瘤细胞浸润和转移中起重要作用.
애자(Ezrin)단백시애자단백、근단백、막돌단백(ezrin-radixin-moesin,ERM)가족중요성원지일,련접우세포막여세포골가지간,재유지세포적형상、겁성、운동이급신호전도방면발휘착중요작용.근년연구발현,애자단백재다수종류세포중이상고표체,재종류암변、종류세포침윤화전이중기중요작용.
Ezrin is a member of ezrin-radixin-moesin(ERM)family acting as correlationship between plasma membrane and cytoskeleton,which plays an important role in maintaining shape,polarity,and movement as well as signal transduction of cells.The recent studies indicate that Ezrin abnormally overexpresses in majority of tumor cells,which has close relationship with carcinogenesis,invading and metastasis of tumor cells.