中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
7期
94-95
,共2页
CA 153%MCA%乳腺癌
CA 153%MCA%乳腺癌
CA 153%MCA%유선암
CA 153%MCA%Breast cancer
目的 探讨CA 153和黏蛋白样癌相关抗原(MCA)在乳腺癌诊治中的应用价值.方法 用ELISA和电化学发光法检测145例对照患者和81例乳腺癌患者的血清CA 153和MCA的水平,并进行比较.结果 145例对照患者CA 153和MCA的检测阳性率分别为15.86%、6.89%,81例乳腺癌患者的CA 153和MCA的检测阳性率为46.91%,33.33%,联检阳性率为55.56%.结论 MCA特异性大于CA 153,但灵敏度不及CA 153,MCA主要用于乳腺癌患者的术后监测和复发转移.MCA和CA 153联合应用可增加诊断的敏感性,优于单一检测,有一定应用价值.
目的 探討CA 153和黏蛋白樣癌相關抗原(MCA)在乳腺癌診治中的應用價值.方法 用ELISA和電化學髮光法檢測145例對照患者和81例乳腺癌患者的血清CA 153和MCA的水平,併進行比較.結果 145例對照患者CA 153和MCA的檢測暘性率分彆為15.86%、6.89%,81例乳腺癌患者的CA 153和MCA的檢測暘性率為46.91%,33.33%,聯檢暘性率為55.56%.結論 MCA特異性大于CA 153,但靈敏度不及CA 153,MCA主要用于乳腺癌患者的術後鑑測和複髮轉移.MCA和CA 153聯閤應用可增加診斷的敏感性,優于單一檢測,有一定應用價值.
목적 탐토CA 153화점단백양암상관항원(MCA)재유선암진치중적응용개치.방법 용ELISA화전화학발광법검측145례대조환자화81례유선암환자적혈청CA 153화MCA적수평,병진행비교.결과 145례대조환자CA 153화MCA적검측양성솔분별위15.86%、6.89%,81례유선암환자적CA 153화MCA적검측양성솔위46.91%,33.33%,련검양성솔위55.56%.결론 MCA특이성대우CA 153,단령민도불급CA 153,MCA주요용우유선암환자적술후감측화복발전이.MCA화CA 153연합응용가증가진단적민감성,우우단일검측,유일정응용개치.
Objective To study the clinical value of serum CA 15-3 and Mucin-like carcinomaassociated antigen (MCA) determination in the diagnosis and treat of breast cancer.Methods The enzymelinked immunosorbent assay(ELISA) and electro-chemical luminescence method were used to detect the serum level of CA 15-3 and MCA in 81 patients with breast cancer,145 control.Results The positive detecting rates of 145 control was 15.86% and 6.89%,the positive detecting rates of 81 patients with breast cancer was 46.91% and 33.33%,in the combined analysis of CA 15-3 and MCA,the positive unite detecting rates was 55.56%.Conclusion Serum MCA determination is very useful for monitor postoperative recurrence and metastasis in breast cancer.The specificity of MCA is higher than CA 15-3,but its sensitivity inferior to CA 15-3.Diagnostic efficiency of combined determination of serum of MCA and CA 153 in the breast cancer was higher than those of the single index.
