CAJ | 학술논문

411例入选者均行OGTT或馒头餐-胰岛素释放试验,并测定空腹胰岛素原.根据FPG水平分为7组.结果显示随FPG升高,HOMA-β功能指数和糖负荷30分钟后净增Ins与净增葡萄糖比值逐渐降低;空腹胰岛素原和空腹胰岛素原/FIns数值逐渐升高;FPG≥8mmol/L,胰岛素曲线下面积逐渐降低.FPG结合FIns测定是反映胰岛β细胞功能的一种简单而实用的方法,对临床处理有指导价值.
411례입선자균행OGTT혹만두찬-이도소석방시험,병측정공복이도소원.근거FPG수평분위7조.결과 현시수FPG승고,HOMA-β공능지수화당부하30분종후정증Ins여정증포도당비치축점강저;공복이도소원화공복이도소원/FIns수치축점승고;FPG≥8mmol/L,이도소곡선하면적축점강저.FPG결합FIns측정시반영이도β세포공능적일충간단이실용적방법,대림상처리유지도개치.
411 subjects were divided into six groups according to their FPG levels.And OGTT was carried out.Result showed that along with the FPG increasing, HOMA β-cell index and ΔI30 /ΔG30 were decreased progressively, and the fasting serum proinsulin level and ratio of proinsulin /insulin were increased markedly.The area under insulin curve decreased gradually when FPG was above 8 mmol/L. In conclusion, FPG is a reflection of islet β cell function.