CAJ | 학술논문

目的探讨比索洛尔与培哚普利联合对慢性心衰患者血浆脑钠肽前体(pro-bnP水平的干预作用.方法选取本院收治的120例慢性心衰患者,随机分为3组,每组40例,即比索洛尔组、培哚普利组和比索洛尔联合培哚普利组,测定治疗前后血浆pro-bnp水平,观察疗效.结果联合治疗组总有效率为95.0%,显著优于比索洛尔组(80.0%)和培哚普利组(77.5%),P＜0.05,治疗后血浆pro-bnp水平联合治疗组显著低于比索洛尔组和培哚普利组,P＜0.05.结论比索洛尔和培哚普利联合用药能够显著降低患者的血浆pro-bnp水平,疗效确切.
목적 탐토비색락이여배타보리연합대만성심쇠환자혈장뇌납태전체(pro-bnP수평적간예작용.방법 선취본원수치적120례만성심쇠환자,수궤분위3조,매조40례,즉비색락이조、배타보리조화비색락이연합배타보리조,측정치료전후혈장pro-bnp수평,관찰료효.결과 연합치료조총유효솔위95.0%,현저우우비색락이조(80.0%)화배타보리조(77.5%),P＜0.05,치료후혈장pro-bnp수평연합치료조현저저우비색락이조화배타보리조,P＜0.05.결론 비색락이화배타보리연합용약능구현저강저환자적혈장pro-bnp수평,료효학절.
Objective To investigate the intervention effect of serum pro-bnp of bisoprolol combined with perindopril in patients with chronic heart failure Methods 120 cases with chronic heart failure of our hospital were randomly divided into 3 groups, bisoprolol group, perindopril group and bisoprolol combined with perindopril group, 40 cases for each group, the serum pro-bnp was determined before and after treatment, observed the curative effect.Results The total effective rate of combined treatment group was 95.0%, that was better than the bisoprolol group (80.0%) and perindopril group (77.5%),P＜0.05 ,after treatment, the level of serum pro-bnp of combined treatment group was less than that of bisoprolol group and perindopril group, P＜0.05.Conclusion bisoprolol combined with perindopril can decrease the level of serum pro-bnp significantly, the curative effect is exact.