CAJ | 학술논문

目的调查冠状动脉旁路移植(coronary artery bypass grafting,CABG)术后患者抑郁焦虑状态的发生率,并分析相关的影响因素.方法以2005年7月至2006年6月在北京大学第一医院心脏外科行择期CABG手术的91例患者为研究对象,术前、术后使用抑郁自评量表和焦虑自评量表进行评分,根据术后是否存在抑郁焦虑状态把患者分成抑郁焦虑组和非抑郁焦虑组.以患者人口学特征、病变程度、合并症以及手术相关特点与术后抑郁焦虑进行相关因素分析.结果 89例患者完成测试,手术后共有41例(46.1%)阳性患者.Logistic退步法回归分析,高脂血症(OR 3.958,95%CI 1.016～7.689)、术前心血管事件(OR 4.285,95%CI 1.051～6.175)、术前脑梗死(OR 3.095,95%CI 0.783～2.426)、术前存在抑郁焦虑症状(OR 13.775,95%CI 2.805～8.207)是术后发生抑郁焦虑的风险因素.结论 CABG术后抑郁焦虑有一定的发生率,需要引起重视,同时高脂血症、术前心血管事件、术前脑梗死、术前存在抑郁焦虑症状可能是术后发生抑郁焦虑的风险因素.
목적 조사관상동맥방로이식(coronary artery bypass grafting,CABG)술후환자억욱초필상태적발생솔,병분석상관적영향인소.방법 이2005년7월지2006년6월재북경대학제일의원심장외과행택기CABG수술적91례환자위연구대상,술전、술후사용억욱자평량표화초필자평량표진행평분,근거술후시부존재억욱초필상태파환자분성억욱초필조화비억욱초필조.이환자인구학특정、병변정도、합병증이급수술상관특점여술후억욱초필진행상관인소분석.결과 89례환자완성측시,수술후공유41례(46.1%)양성환자.Logistic퇴보법회귀분석,고지혈증(OR 3.958,95%CI 1.016～7.689)、술전심혈관사건(OR 4.285,95%CI 1.051～6.175)、술전뇌경사(OR 3.095,95%CI 0.783～2.426)、술전존재억욱초필증상(OR 13.775,95%CI 2.805～8.207)시술후발생억욱초필적풍험인소.결론 CABG술후억욱초필유일정적발생솔,수요인기중시,동시고지혈증、술전심혈관사건、술전뇌경사、술전존재억욱초필증상가능시술후발생억욱초필적풍험인소.
Objective To investigate the incidence of depression and anxiety post-operation of coronary artery bypass grafting(CABG)and analysis the correlated factor.Methods 91 patients underwent scheduled CABG in the first hospital of Peking University from July 2005 to June 2006.The patients were interviewed to assess depression and anxiety symptoms using self-rating depression scale(SDS)and self-rating anxiety scale(SAS)before operation and before discharge.The patients were divided into depression and anxiety group and no depression and anxiety group according to with or without depression and anxiety.Demography characteristic,medical,surgical risk factors were assessed during suery.Results 89 patients completed evaluation.41 patients (46.1%)had depression and/or anxiety symptoms after CABG.Hyperlipemia(OR 3.958,95%CI 1.016～7.689),heart blood vesse]event(OR4.285,95%CI 1.051～6.175),depression and anxiety(OR 3.095,95%CI 0.783～2.426),cerebral infarction(OR 13.775,95%CI 2.805～8.207)before operation ale risk factors for depression and anxiety post surgery.Conclusion The incidence rate of depression and anxiety post CABG is hish and should be paid more attention.Hyperlipemia,heart blood vessel event,depression and anxiety,cerebral infarction before operation ale possible risk factors for depression and anxiety post smgery.