CAJ | 학술논문

目的观察研究正常及声带良恶性增生疾病嗓音声学特征，探讨计算机声学测试技术在喉疾病鉴别诊断及预后观察中的应用价值。方法采用计算机嗓音声学测试系统对80例正常成人及140例声带良恶性增生疾病患者元音信号进行检测，对频率微扰（jitter）、振幅微扰（shimmer）、声门噪声能量（NNE）等进行分析。结果 140例病态嗓音均表现一项或几项声学参数值高于正常，各参数均值较正常值差别有统计学意义。声带良性增生组jitter值大于正常者占24％，shimmer占83％，NNE占58％；各参数均值较正常值约升高1～1.5倍左右。声带不典型增生组jitter值异常者占56％，shimmer值占90％，NNE值占74％；各参数均值较正常升高1～2.5倍。喉癌组jitter、shimmer、NNE值高于正常者分别占87％、94％、90％；各参数均值较正常值升高4.5～5倍左右。结论计算机声学分析各项参数可作为嗓音定量评价的客观指标，有助于喉部病变性质的初步鉴别及动态观察预后。
목적관찰연구정상급성대량악성증생질병상음성학특정，탐토계산궤성학측시기술재후질병감별진단급예후관찰중적응용개치。방법채용계산궤상음성학측시계통대80례정상성인급140례성대량악성증생질병환자원음신호진행검측，대빈솔미우（jitter）、진폭미우（shimmer）、성문조성능량（NNE）등진행분석。결과 140례병태상음균표현일항혹궤항성학삼수치고우정상，각삼수균치교정상치차별유통계학의의。성대량성증생조jitter치대우정상자점24％，shimmer점83％，NNE점58％；각삼수균치교정상치약승고1～1.5배좌우。성대불전형증생조jitter치이상자점56％，shimmer치점90％，NNE치점74％；각삼수균치교정상승고1～2.5배。후암조jitter、shimmer、NNE치고우정상자분별점87％、94％、90％；각삼수균치교정상치승고4.5～5배좌우。결론계산궤성학분석각항삼수가작위상음정량평개적객관지표，유조우후부병변성질적초보감별급동태관찰예후。
Objective　To investigate the characteristics of acoustic parameters of benign and malignant diseases of vocal cords and discuss the value of acoustic analysis technique by computer in the objective differentiation and prognosis of the laryngeal diseases．Methods　The voice signals of sustained vowel“a” were measured with a micro-computer in 80 healthy adults and 140 patients with varying benign and malignant diseases of vocal cords．The acoustic parameters （jitter，shimmer and NNE） were analyzed and compared．Results　The acoustic parameters were significantly increased in all patients with benign and malignant diseases of vocal cords．The mean parameters were 1-1.5 times in benign diseases，1-2.5 times in atypical hyperplasia，and 4.5-5 times in carcinoma higher than the control group．Conclusion　The acoustic parameters can be used as objective standards for evaluating voice function quantitatively．The acoustic analysis by computer is of value in the objective differentiation and prognosis observation of the laryngeal diseases．