CAJ | 학술논문

谷胱甘肽S-转移酶(glutathione S-transferascs,GSTs,E.C.2.5.1.18)是由多个基因编码、具有多种功能的超家族酶,广泛存在于动物、植物、微生物等多种生物组织中.在生物体遇到高盐、干旱、除草剂、有机污染物等逆境时,GSTs常发挥其Ⅱ相代谢酶和抗氧化酶的双重功能,以保护生物体免受逆境的损害.文章综述了GSTs的分类、结构、功能、应用及克隆表达等方面的研究进展.
곡광감태S-전이매(glutathione S-transferascs,GSTs,E.C.2.5.1.18)시유다개기인편마、구유다충공능적초가족매,엄범존재우동물、식물、미생물등다충생물조직중.재생물체우도고염、간한、제초제、유궤오염물등역경시,GSTs상발휘기Ⅱ상대사매화항양화매적쌍중공능,이보호생물체면수역경적손해.문장종술료GSTs적분류、결구、공능、응용급극륭표체등방면적연구진전.
This paper reviews current aspects in the study of glutathione S -transferases in terms of the classification,structure, application, function and cloning/expression. Glutathione S-transferases (GSTs, EC 2.5.1.18), encoded-by multi-genes, belong to a sort of super-family enzyme of multifunctional protein widely existing in animal, plants and microbes.GSTs could play a dual role in the cellular metabolism/detoxification which is characterized by the anti-oxidation against reactive oxygen species (ROS) caused by harsh environmental stress, induding high salt, drought, and contamination of herbicides and other organic pollutants.