CAJ | 학술논문

目的探讨左旋卡尼汀对血液透析患者生存质量的改善作用.方法采用随机、对照的研究方法 ,选择本院血透室透析一年以上的维持性血液透析患者60例,将患者随机分为观察组33例和对照组27例,并给观察组每次透析后静脉注射左卡尼汀1g,两组患者其余治疗方案相同.观察过程共12周.结果治疗后观察组患者的主观症状明显改善(P<0.05);营养状态明显优于对照组(P<0.05);其血 C反应蛋白、磷酸肌酸激酶等指标的水平显著低于对照组(P<0.05).而治疗前两组患者的相关指标无显著性差异(P>0.05).结论长期使用左卡尼汀能改善血液透析患者的生存质量.
목적 탐토좌선잡니정대혈액투석환자생존질량적개선작용.방법 채용수궤、대조적연구방법 ,선택본원혈투실투석일년이상적유지성혈액투석환자60례,장환자수궤분위관찰조33례화대조조27례,병급관찰조매차투석후정맥주사좌잡니정1g,량조환자기여치료방안상동.관찰과정공12주.결과 치료후관찰조환자적주관증상명현개선(P<0.05);영양상태명현우우대조조(P<0.05);기혈 C반응단백、린산기산격매등지표적수평현저저우대조조(P<0.05).이치료전량조환자적상관지표무현저성차이(P>0.05).결론 장기사용좌잡니정능개선혈액투석환자적생존질량.
Objectives To investigate L-carnitine on mainteace hemodialysis patients' living quality.Methods sixty maintenee hemedialysis.patients were randomized into two groups:treatment group(n = 33) and control group(n = 27). In treatment group, 1 g of L-carnitine was infused to the patients at the end of each hemodial-ysis treatment for 12 weeks. Other treatment projection of two groups were. Equal. Results In treatment group, the subjective symptoms and nutritional status were improved shile blood CRP,CPK and other items were decreased with a signifieant difference between control group after treatment. Conclusions L-carnifine can improve hemodialy-sis patients' living quality.