中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2008年
4期
531-532,插图4-1
,共3页
刘芳%潘昱%赖均鹏%刘应时
劉芳%潘昱%賴均鵬%劉應時
류방%반욱%뢰균붕%류응시
涎腺肿瘤%腺瘤%多形性%抗原,CD44
涎腺腫瘤%腺瘤%多形性%抗原,CD44
연선종류%선류%다형성%항원,CD44
Salivary gland neoplasms%Adenoma%Pleomorphic%Antigens,CD44
目的 探讨CD44不同变异体在涎腺多形性腺瘤中表达及意义.方法 应用免疫组织化学方法检测30例涎腺多形性腺瘤CD44v3、CD44v6的表达.结果 CD44v3在涎腺多形性腺瘤阳性(66.7%)表达,CD44v6在涎腺多形性腺瘤中呈强阳性表达(86.7%).结论 CD44v3、CD44v6在涎腺多形性腺瘤呈阳性表达,提示瘤细胞粘附力较强,可能是涎腺多形性腺瘤不易发生转移的原因.
目的 探討CD44不同變異體在涎腺多形性腺瘤中錶達及意義.方法 應用免疫組織化學方法檢測30例涎腺多形性腺瘤CD44v3、CD44v6的錶達.結果 CD44v3在涎腺多形性腺瘤暘性(66.7%)錶達,CD44v6在涎腺多形性腺瘤中呈彊暘性錶達(86.7%).結論 CD44v3、CD44v6在涎腺多形性腺瘤呈暘性錶達,提示瘤細胞粘附力較彊,可能是涎腺多形性腺瘤不易髮生轉移的原因.
목적 탐토CD44불동변이체재연선다형성선류중표체급의의.방법 응용면역조직화학방법검측30례연선다형성선류CD44v3、CD44v6적표체.결과 CD44v3재연선다형성선류양성(66.7%)표체,CD44v6재연선다형성선류중정강양성표체(86.7%).결론 CD44v3、CD44v6재연선다형성선류정양성표체,제시류세포점부력교강,가능시연선다형성선류불역발생전이적원인.
Objective To investigate the expression of CD44v3 and CD44v6 in the polymorphic adenoma of salivary glands. Methods Using immunohistochemistry technology to detect the expression of CD44v3 and CD44v6 in 30 cases of polymorphic adenoma of salivary glands. Results The expression of CD44v3 was positive in 66.7 %cases within 30 paraffin-embedded sections, while CD44v6,86.7 % was positive. Conclusion The high expression of CD44v3 and CD44v6 maybe the reason of the low invasive ability and migration of polymorphic adenoma of salivary glands.
