CAJ | 학술논문

目的探讨中老年人自身免疫性胰腺炎(AIP)的磁共振(MRI)特征. 方法 17例经组织学或类固醇激素治疗证实的中老年AIP患者,均接受MRI检查,对患者的临床和MRI资料进行回顾性分析. 结果 17例中老年AIP中,13例AIP表现为胰腺弥漫性肿大,4例为局限性肿大或局限性信号异常.病变T_1WI上呈明显低信号,在T_2WI上呈轻度高信号,动脉期强化减弱但呈现明显的延时强化.13例在胰腺病变周围环绕包膜样结构.15例AIP伴有胰腺段胆总管的狭窄,5例胰胆管磁共振显示胰管不规则狭窄.11例AIP的平均表观扩散系数值为1.64×10~3mm~2/s. 结论 AIP好发于中老年人;其MRI特征包括胰腺呈香肠样或香蕉样肿大、病变胰腺周围延迟强化的包膜样影、胰管弥漫不规则狭窄等,MRI既可用于诊断AIP,也是评价其疗效的重要手段.
목적 탐토중노년인자신면역성이선염(AIP)적자공진(MRI)특정. 방법 17례경조직학혹류고순격소치료증실적중노년AIP환자,균접수MRI검사,대환자적림상화MRI자료진행회고성분석. 결과 17례중노년AIP중,13례AIP표현위이선미만성종대,4례위국한성종대혹국한성신호이상.병변T_1WI상정명현저신호,재T_2WI상정경도고신호,동맥기강화감약단정현명현적연시강화.13례재이선병변주위배요포막양결구.15례AIP반유이선단담총관적협착,5례이담관자공진현시이관불규칙협착.11례AIP적평균표관확산계수치위1.64×10~3mm~2/s. 결론 AIP호발우중노년인;기MRI특정포괄이선정향장양혹향초양종대、병변이선주위연지강화적포막양영、이관미만불규칙협착등,MRI기가용우진단AIP,야시평개기료효적중요수단.
Objective To investigate magnetic resonance imaging(MRI) characteristics of autoimmune pancreatitis(AIP) in middle-aged and elderly patients. Methods MRI were performed in 17 middle-aged and elderly patients with AlP proved histopathologically or clinically. All clinical and MRI data were reviewed. Results Of 17 cases, MRI showed diffuse enlargement of the pancreas in 13 cases, and focal lesions in 4 cases. Swelled pancreas was hypointense on T1-weighted images, mildly hyperintense on T2-weighted images, decreased enhancement on artery phase of dynamic imaging, and moderate enhancement on delayed phase images. Capsule-like enhanced rim was found around swelled pancreas in 13 patients. Stricture of distal common bile duct was present in 15 patients, and diffuse irregular narrowing of the main pancreatic duct was showed in 5 cases. The mean apparent diffusion coefficient(ADC) value of AIP was 1.64×10~(-3) mm~2/s in 13 cases. Conclusions AIP occurs more often in middle-aged and elderly people. AIP shows some characterized MRI findings including swelled pancreas looking like banana or sausage, delayed enhanced capsule-like rim around the lesion and diffuse irregular narrowing of pancreatic duct. MRI will play an important role not only in the diagnosis of AIP, but also in evaluating curative effect of AIP.