CAJ | 학술논문

本文根据“肾主骨”的中医理论,探讨了益肾补骨推拿法治疗骨质疏松症模型动物的实验方法.常用的模型制作方法包括卵巢摘除骨质疏松大鼠模型(OVX)、老年性骨质疏松大鼠模型和糖皮质激素诱发骨质疏松大鼠模型( GIOP),对这些造模成功的大鼠进行益肾补骨推拿法操作,观测大鼠骨密度(BMD)和骨代谢生化指标的变化.通过动物实验证实,益肾补骨推拿法对骨质疏松模型大鼠均有效,为益肾补骨推拿法治疗骨质疏松症的临床研究提供理论依据和方法学参考.
본문근거“신주골”적중의이론,탐토료익신보골추나법치료골질소송증모형동물적실험방법.상용적모형제작방법포괄란소적제골질소송대서모형(OVX)、노년성골질소송대서모형화당피질격소유발골질소송대서모형( GIOP),대저사조모성공적대서진행익신보골추나법조작,관측대서골밀도(BMD)화골대사생화지표적변화.통과동물실험증실,익신보골추나법대골질소송모형대서균유효,위익신보골추나법치료골질소송증적림상연구제공이론의거화방법학삼고.
Based on the "kidney controlling bones" of traditional Chinese medicine theory,this article researched the effects of treating osteoporosis with the method of kidney-tonifying and bone-strengthening massage therapy.Commonly used method of modeling included ovariectomized rat model of osteoporosis (OVX),senile rat model of osteoporosis and glucocorticoid induced rat model of osteoporosis (GIOP),kidney-tonifying and bone-strengthening massage therapy were applied on these models,and the rat bone mineral density (BMD) and biochemical marker of bone metabolism changes were observed.Confirmed by animals experiment,it was effective to repair a bone in all rat osteoporosis models with kidney-tonifying and bone-strengthening massage,which provided theoretical basis and methodological guidance for the use of kidney-tonifying and bone-strengthening massage therapy in the clinical treatment of osteoporosis.