CAJ | 학술논문

慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)是进行性加重的、不完全可逆性通气气流受限为主要特征的一种肺部炎症性疾病,COPD已经成为全球重大卫生问题,其发病机制尚不完全明确,但近期研究提示COPD的发病机制与自身异常的免疫反应有关.这一发现推动了COPD疾病预防、诊断、治疗及预后判断等方面的研究取得新的进展.
만성조새성폐질병(chronic obstructive pulmonary disease,COPD)시진행성가중적、불완전가역성통기기류수한위주요특정적일충폐부염증성질병,COPD이경성위전구중대위생문제,기발병궤제상불완전명학,단근기연구제시COPD적발병궤제여자신이상적면역반응유관.저일발현추동료COPD질병예방、진단、치료급예후판단등방면적연구취득신적진전.
Chronic obstructive pulmonary disease (COPD) is a disease state characterized by airflow limitation that is not fully reversible,and the airflow limitation is usually progressive. Yet COPD is a major worldwide medical problem,and its pathogenesis can not be completely understood. A growing body of evidences indicate that autoimmune responses may play a role in the pathogenesis of inflammation of COPD. These studies have substantial relevance for future development of precaution, diagnosis,management and prognosis of this disease.