中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2010年
19期
23-25
,共3页
社区获得性肺炎%莫西沙星%左氧氟沙星
社區穫得性肺炎%莫西沙星%左氧氟沙星
사구획득성폐염%막서사성%좌양불사성
Community-acquired pneumonia%Moxifloxacin%Levofloxacin
目的 观察门诊口服莫西沙星片剂治疗社区获得性肺炎(CAP)患者的疗效及安全性.方法 收集符合试验标准的CAP患者110例,采用随机分组法分成治疗组56例和对照组54例,治疗组门诊口服莫西沙星片治疗,对照组应用门诊静脉点滴左氧氟沙星注射液治疗,观察两组临床及细菌学疗效及不良反应.结果 治疗组总临床有效率为94.6%,细菌清除率为90.0%,与药物有关的不良事件发生率为7.1%.对照组总临床有效率为92.6%,细菌清除率为90.2%,不良反应发生率为18.5%.两组比较差异均无统计学意义(P>0.05).结论 门诊口服莫西沙星治疗社区获得性肺炎简单、安全、有效.
目的 觀察門診口服莫西沙星片劑治療社區穫得性肺炎(CAP)患者的療效及安全性.方法 收集符閤試驗標準的CAP患者110例,採用隨機分組法分成治療組56例和對照組54例,治療組門診口服莫西沙星片治療,對照組應用門診靜脈點滴左氧氟沙星註射液治療,觀察兩組臨床及細菌學療效及不良反應.結果 治療組總臨床有效率為94.6%,細菌清除率為90.0%,與藥物有關的不良事件髮生率為7.1%.對照組總臨床有效率為92.6%,細菌清除率為90.2%,不良反應髮生率為18.5%.兩組比較差異均無統計學意義(P>0.05).結論 門診口服莫西沙星治療社區穫得性肺炎簡單、安全、有效.
목적 관찰문진구복막서사성편제치료사구획득성폐염(CAP)환자적료효급안전성.방법 수집부합시험표준적CAP환자110례,채용수궤분조법분성치료조56례화대조조54례,치료조문진구복막서사성편치료,대조조응용문진정맥점적좌양불사성주사액치료,관찰량조림상급세균학료효급불량반응.결과 치료조총림상유효솔위94.6%,세균청제솔위90.0%,여약물유관적불량사건발생솔위7.1%.대조조총림상유효솔위92.6%,세균청제솔위90.2%,불량반응발생솔위18.5%.량조비교차이균무통계학의의(P>0.05).결론 문진구복막서사성치료사구획득성폐염간단、안전、유효.
Objective To observe the efficacy and safety of oral moxifloxacin in the treatment of outpatients with community-acquired pneumonia. Methods Fifty-six cases of community-acquired pneumonia patients used oral moxifloxacin. Meanwhile, the other 60 cases of patients used intravenous levofloxacin. Clinic index,bacterium clearance,curative effect and safety were observed. Results The clinical efficacy in the trial and control group were 94.6% and 92.6% respectively,and the bacterial eradication rates were 90.0% and 90.2%, The adverse drug reaction rates were evaluated in all patients, showing the rates were 7.1% and 18.5%. Conclusions Oral moxifloxacin is effective,simple and safe in the treatment of outpatients with community-acquired pneumonia.
