中国地方病学杂志
中國地方病學雜誌
중국지방병학잡지
CHINESE JOURNAL OF ENDEMIOLOGY
2008年
2期
152-153
,共2页
薛建江%李立宏%乔海霞%刘进军%季建军%张玉妥%杨瑞馥%邱景富
薛建江%李立宏%喬海霞%劉進軍%季建軍%張玉妥%楊瑞馥%邱景富
설건강%리립굉%교해하%류진군%계건군%장옥타%양서복%구경부
耶尔森菌,鼠疫%微生物敏感性试验%抗菌药
耶爾森菌,鼠疫%微生物敏感性試驗%抗菌藥
야이삼균,서역%미생물민감성시험%항균약
Yersinia pestis%Microbial sensitivity tests%Anti-bacterial agents
目的 观察6种抗菌中药对鼠疫菌的抑菌活性作用.方法 选择6种(黄连、苦参、连翘、大黄、生地、知母)常用抗菌中药,分别采用水提法制备至质量浓度1 mg/L的药液.应用液体稀释法测定上述中药对鼠疫菌201株与EV76株的最低抑菌浓度(MIC).结果 黄连、大黄与连翘抑制鼠疫菌的作用均较强,MIC值均≤0.050 00 mg/L,其中大黄的抑菌作用最强(MIC值为0/025 00 mg/L).同一种中药对鼠疫菌不同菌株的MIC值相同.结论 常用抗菌中药对鼠疫菌有一定的抑菌作用.
目的 觀察6種抗菌中藥對鼠疫菌的抑菌活性作用.方法 選擇6種(黃連、苦參、連翹、大黃、生地、知母)常用抗菌中藥,分彆採用水提法製備至質量濃度1 mg/L的藥液.應用液體稀釋法測定上述中藥對鼠疫菌201株與EV76株的最低抑菌濃度(MIC).結果 黃連、大黃與連翹抑製鼠疫菌的作用均較彊,MIC值均≤0.050 00 mg/L,其中大黃的抑菌作用最彊(MIC值為0/025 00 mg/L).同一種中藥對鼠疫菌不同菌株的MIC值相同.結論 常用抗菌中藥對鼠疫菌有一定的抑菌作用.
목적 관찰6충항균중약대서역균적억균활성작용.방법 선택6충(황련、고삼、련교、대황、생지、지모)상용항균중약,분별채용수제법제비지질량농도1 mg/L적약액.응용액체희석법측정상술중약대서역균201주여EV76주적최저억균농도(MIC).결과 황련、대황여련교억제서역균적작용균교강,MIC치균≤0.050 00 mg/L,기중대황적억균작용최강(MIC치위0/025 00 mg/L).동일충중약대서역균불동균주적MIC치상동.결론 상용항균중약대서역균유일정적억균작용.
Objective To screen the antibacterial activity of Chinese traditional medicines against Yersinia pestis.Methods Six Chinese traditional medicines(Coptis Chinesis etc)were selected and extracted with pure water to make a concentration of 1 mg/L.Yersinia pestis strain 201 and EV 76 were used to determine the minimal inhibitory concentrations(MIC)of these selected medicines in vitro with liquid dilution method.Results Three herbs had inhibition effects on the strain 201 and EV76 in different extents,among which Rheum palmatum had the strongest effect and MIC was 0.025 00 mg/L.Furthermore,the Chinese traditional medicine had the same MIC on both strain 201 and EV76.Conclusions Chinese traditional medicines commonly used have inhibiting effect on Yersinia pesti.
