CAJ | 학술논문

目的探讨早产儿血清铁蛋白、叶酸、维生素B12(贫血3项)的变化情况,以便及早采取干预措施,预防和治疗早产儿贫血.方法完全随机选取住院的早产儿30例作为观察组,正常新生儿30例为对照组.采用电发光分析仪,分别对2组对象进行贫血3项检测和比较.结果早产儿出生时血清铁蛋白为(159.2±83.2)μg/L,低于对照组的(334.4±150.5)μg/L,差异有统计学意义(P＜0.05);维生素B12(383.5±236.4)ng/L与对照组(502.4±168.8)ng/L比较差异亦有统计学意义(P＜0.01).2周后检测,早产儿叶酸与出生时比较有明显下降[(17.1±2.2)μg/L比(13.1±3.9)μg/L,P＜0.01],维生素B12(248.8±205.4)ng/L也有明显下降(P＜0.05);红细胞总数、血红蛋白以及红细胞平均压积亦明显下降(P＜0.05).结论早产儿出生后体内血清铁蛋白和维生素B12处于低水平;叶酸、维生素B12水平随着日龄的增加逐渐减低.
목적 탐토조산인혈청철단백、협산、유생소B12(빈혈3항)적변화정황,이편급조채취간예조시,예방화치료조산인빈혈.방법 완전수궤선취주원적조산인30례작위관찰조,정상신생인30례위대조조.채용전발광분석의,분별대2조대상진행빈혈3항검측화비교.결과 조산인출생시혈청철단백위(159.2±83.2)μg/L,저우대조조적(334.4±150.5)μg/L,차이유통계학의의(P＜0.05);유생소B12(383.5±236.4)ng/L여대조조(502.4±168.8)ng/L비교차이역유통계학의의(P＜0.01).2주후검측,조산인협산여출생시비교유명현하강[(17.1±2.2)μg/L비(13.1±3.9)μg/L,P＜0.01],유생소B12(248.8±205.4)ng/L야유명현하강(P＜0.05);홍세포총수、혈홍단백이급홍세포평균압적역명현하강(P＜0.05).결론 조산인출생후체내혈청철단백화유생소B12처우저수평;협산、유생소B12수평수착일령적증가축점감저.
Objective To investigate the level changes of serum ferritin, folacin and vitamin B12 in prematurity. Methods Thirty prematurities and 30 healthy newborn babies were were enrolled in this study. Serum ferritin, folacin and vitamin B12 were measured by using electroluminescence analyzer. Results The serum ferritin and vitamin B12 of prematurity were lower than those of normal newborn babies [( 159.2 ± 83.2) μg/L vs (334.4 ±150.5 ) μg/L, P ＜ 0.05; ( 383.5 ± 236.4 ) ng/L vs (502.4 ± 168.8 ) ng/L, P ＜ 0. 01]. Serum ferritin and vitamin B12 of prematurity decreased after 2 weeks[(17. 1 ±2.2)μg/L vs (13.1 ±3.9) μg/L, P＜0.01;(383.5 ±236.4)ng/L vs (248.8 ±205.4)ng/L, P ＜0.05]. Conclusions After birth, serum ferritin and vitamin B12 of prematurity are at a low level. Folacin and vitamin Bi2 decrease with the increase of age.