中华实验和临床病毒学杂志
中華實驗和臨床病毒學雜誌
중화실험화림상병독학잡지
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY
2010年
1期
68-70
,共3页
单平囡%卢志勇%宣国红%翁利民%茹金城%谈素红%许德顺
單平囡%盧誌勇%宣國紅%翁利民%茹金城%談素紅%許德順
단평닙%로지용%선국홍%옹이민%여금성%담소홍%허덕순
肝炎表面抗原,乙型%肝炎病毒,乙肝%DNA%敏感性与特异性
肝炎錶麵抗原,乙型%肝炎病毒,乙肝%DNA%敏感性與特異性
간염표면항원,을형%간염병독,을간%DNA%민감성여특이성
Hepatitis B surface antigens%Hepaitis B virus%DNA%Sensitivity and Specificity
目的 检测乙肝患者的HBV-LP及HBV DNA,探讨HBV-LP的敏感性和特异性及其临床应用价值.方法 HBV-LP检测采用ELISA法,HBV DNA检测采用RT-PCR法.结果 HBV-LP检测及HBV DNA检测的敏感性分别为64.89%、99.68%和60.63%、100%(P>0.05);两检测的+LR和-LR分别为202.78、60.63和0.3522、0.3937,+LR之间差异有统计学意义(P<0.005).结论 HBV-LP检测有与HBV DNA检测相近的敏感性及特异性,阳性似然比更高于HBV DNA检测,为较好的检测HBV DNA复制的血清学指标.
目的 檢測乙肝患者的HBV-LP及HBV DNA,探討HBV-LP的敏感性和特異性及其臨床應用價值.方法 HBV-LP檢測採用ELISA法,HBV DNA檢測採用RT-PCR法.結果 HBV-LP檢測及HBV DNA檢測的敏感性分彆為64.89%、99.68%和60.63%、100%(P>0.05);兩檢測的+LR和-LR分彆為202.78、60.63和0.3522、0.3937,+LR之間差異有統計學意義(P<0.005).結論 HBV-LP檢測有與HBV DNA檢測相近的敏感性及特異性,暘性似然比更高于HBV DNA檢測,為較好的檢測HBV DNA複製的血清學指標.
목적 검측을간환자적HBV-LP급HBV DNA,탐토HBV-LP적민감성화특이성급기림상응용개치.방법 HBV-LP검측채용ELISA법,HBV DNA검측채용RT-PCR법.결과 HBV-LP검측급HBV DNA검측적민감성분별위64.89%、99.68%화60.63%、100%(P>0.05);량검측적+LR화-LR분별위202.78、60.63화0.3522、0.3937,+LR지간차이유통계학의의(P<0.005).결론 HBV-LP검측유여HBV DNA검측상근적민감성급특이성,양성사연비경고우HBV DNA검측,위교호적검측HBV DNA복제적혈청학지표.
Objective To detect HBV-LP and HBV DNA of the patients with hepatitis B, and to study the sensitive and specificity of HBV-LP detecting and its evaluate on for clinical application. Methods The ELISA was used for HBV-LP detecting and RT-PCR for HBV DNA detecting. Results The sensitive and specificity of HBV-LP and HBV DNA were 64.89% ,99.68% ,60.63% and 100% respectively(P > 0.05);+LR, -LR were 202.78,60.63, 0.3522 and 0.3937, and there were significance between +LR of the detecting (P<0.005 ). Conclusion The sensitive and specificity of HBV-LP and HBV DNA detecting are considerable, +LRof HBV-LP are higher comparing HBV DNA. The HBV-LP is better serology index for detecting replication of HBV DNA.
