CAJ | 학술논문

钩端螺旋体病是一种在世界范围内传播的重要的人兽共患病.钩端螺旋体(钩体)感染机体后,固有免疫在早期控制感染扩散中的作用及意义逐渐受到重视.巨噬细胞对钩体具有吞噬和杀伤作用,同时,致病性钩体可逃避巨噬细胞杀伤.中性粒细胞、补体系统和细胞因子在抵御钩体感染方面也具有一定的作用.
구단라선체병시일충재세계범위내전파적중요적인수공환병.구단라선체(구체)감염궤체후,고유면역재조기공제감염확산중적작용급의의축점수도중시.거서세포대구체구유탄서화살상작용,동시,치병성구체가도피거서세포살상.중성립세포、보체계통화세포인자재저어구체감염방면야구유일정적작용.
Leptospirosis is an important zoonosis with worldwide distribution. As the first procedure in immunity system, the role and significance of innate immunity in controlling infection at the early stage of the disease have gradually been emphasized. Macrophages can phagocytize and kill leptospira, while the pathogenic leptospira can evade the killing by macrophages. In addition, neutrophils, complement system and cytokines also contribute to the defence of leptospira infection.