临床麻醉学杂志
臨床痳醉學雜誌
림상마취학잡지
THE JOURNAL OF CLINICAL ANESTHESIOLOGY
2010年
3期
224-226
,共3页
肢体缺血-再灌注损伤%凝血功能%血栓弹力描记图
肢體缺血-再灌註損傷%凝血功能%血栓彈力描記圖
지체결혈-재관주손상%응혈공능%혈전탄력묘기도
Ischemia-reperfusion injury of the limbs%Blood coagulation%Thrombelastography
目的 探讨肢体缺血-再灌注损伤(I-RI)对患者凝血功能的影响.方法 18例择期在硬膜外麻醉下行单侧膝关节镜手术治疗患者,术中使用充气式止血带,肢体缺血时间(42±6)min.分别于止血带充气前(T_1)、肢体缺血30 min(T_2)、再灌注3 min(T_3和30 min(T_4)抽取静脉血,应用血栓弹力描记图(TEG)检测凝血功能.结果 与T_1时比较,TEG显示反应时间(R值)和凝同时间(K值)降低、凝固角(α角)和血栓最大幅度(MA值)增大,但其改变均在正常值范围,且与其他时点相比差异无统计学意义.结论 肢体I-RI对患者凝血功能没有显著影响.
目的 探討肢體缺血-再灌註損傷(I-RI)對患者凝血功能的影響.方法 18例擇期在硬膜外痳醉下行單側膝關節鏡手術治療患者,術中使用充氣式止血帶,肢體缺血時間(42±6)min.分彆于止血帶充氣前(T_1)、肢體缺血30 min(T_2)、再灌註3 min(T_3和30 min(T_4)抽取靜脈血,應用血栓彈力描記圖(TEG)檢測凝血功能.結果 與T_1時比較,TEG顯示反應時間(R值)和凝同時間(K值)降低、凝固角(α角)和血栓最大幅度(MA值)增大,但其改變均在正常值範圍,且與其他時點相比差異無統計學意義.結論 肢體I-RI對患者凝血功能沒有顯著影響.
목적 탐토지체결혈-재관주손상(I-RI)대환자응혈공능적영향.방법 18례택기재경막외마취하행단측슬관절경수술치료환자,술중사용충기식지혈대,지체결혈시간(42±6)min.분별우지혈대충기전(T_1)、지체결혈30 min(T_2)、재관주3 min(T_3화30 min(T_4)추취정맥혈,응용혈전탄력묘기도(TEG)검측응혈공능.결과 여T_1시비교,TEG현시반응시간(R치)화응동시간(K치)강저、응고각(α각)화혈전최대폭도(MA치)증대,단기개변균재정상치범위,차여기타시점상비차이무통계학의의.결론 지체I-RI대환자응혈공능몰유현저영향.
Objective To investigate the effects of limb ischemia-reperfusion injury(I-RI) on blood coagulation.Methods Eighteen patients scheduled for unilateral knee arthroscopy surgery under epidural anesthesia were treated with an inflatable tourniquet to ptoduce ischemia for (42 ± 6) min.Venous blood was taken before tourniquet inflation,at 30 min during ischemia,3 min and 30 min during reperfusion for measuring blood coagulation by thrombelastography(TEG).Results TEG showed the decreases in reaction time(R value) and coagulation time(K value),and the increases in alpha angle(α) and maximal amplitude(MA),which were all within the normal limits and had no significant differences among four time points of testing.Conclusion I-RI of the limbs has no significant effects on blood coagulation.
