河北化工
河北化工
하북화공
HEBEI CHEMICAL ENGINEERING AND INDUSTRY
2011年
9期
16-17,63
,共3页
顶空气相色谱%毛细管柱%甲钴胺%丙酮%乙醇%残留量
頂空氣相色譜%毛細管柱%甲鈷胺%丙酮%乙醇%殘留量
정공기상색보%모세관주%갑고알%병동%을순%잔류량
headspace gas chromatography%capillary column%mecobalamin%acetone%ethanol%vesidue
采用毛细管顶空气相色谱法测定甲钴胺中有机溶剂残留量。采用带自动顶空进样器的气相色谱仪,Rtx？-624毛细管色谱柱,以丙酮及乙醇为标准品,外标法进行定量。乙醇在2.192×10-5～1.534 4×10-4的范围内线性关系良好（r=0.999 5）,回收率达到94.54%～108.40%,检测限为2.19×10-6,定量限为1.096×10-5;丙酮在2.28×10-5～1.596×10-4的范围内线性关系良好（r=0.999 7）,回收率达到92.11%～108.09%,检测限为5.7×10-8,定量限为2.28×10-7。
採用毛細管頂空氣相色譜法測定甲鈷胺中有機溶劑殘留量。採用帶自動頂空進樣器的氣相色譜儀,Rtx？-624毛細管色譜柱,以丙酮及乙醇為標準品,外標法進行定量。乙醇在2.192×10-5～1.534 4×10-4的範圍內線性關繫良好（r=0.999 5）,迴收率達到94.54%～108.40%,檢測限為2.19×10-6,定量限為1.096×10-5;丙酮在2.28×10-5～1.596×10-4的範圍內線性關繫良好（r=0.999 7）,迴收率達到92.11%～108.09%,檢測限為5.7×10-8,定量限為2.28×10-7。
채용모세관정공기상색보법측정갑고알중유궤용제잔류량。채용대자동정공진양기적기상색보의,Rtx？-624모세관색보주,이병동급을순위표준품,외표법진행정량。을순재2.192×10-5～1.534 4×10-4적범위내선성관계량호（r=0.999 5）,회수솔체도94.54%～108.40%,검측한위2.19×10-6,정량한위1.096×10-5;병동재2.28×10-5～1.596×10-4적범위내선성관계량호（r=0.999 7）,회수솔체도92.11%～108.09%,검측한위5.7×10-8,정량한위2.28×10-7。
To determine the content of solvent residues in mecobalamin by capillary headspace gas chromatography meth-od with headspace sample injector.The capillary chromatographic column is Rtx-624.With ethanol and acetone as stan-dard substance,external standard method for quantitative,the linear relationship of ethanol（2.192×10-5 ～1.534 4×10-4）（r = 0.999 5）was good,the recovery was 94.54% ～108.40%,limit of detection（LOD） was 2.19×10-6,limit of quantitation（LOQ） was 1.096×10-5.The linear relationship of acetone（2.28×10-5 ～1.596×10-4）（r = 0.999 7）was good,the recovery was 92.11% ～108.09%,LOD was 5.7×10-8,LOQ was 2.28×10-7.
