中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2009年
8期
81-82
,共2页
子宫内膜透明细胞癌%血管内皮生长因子%免疫组化%生存时间
子宮內膜透明細胞癌%血管內皮生長因子%免疫組化%生存時間
자궁내막투명세포암%혈관내피생장인자%면역조화%생존시간
Uterine endometrial clear cell carcinoma%Vascular endothelial growth factor%Immunohistochemistry%Survival time
目的 研究子宫内膜透明细胞癌ECCC(uterine endometrial clear cell carcinoma,ECCC)组织中血管内皮生长因子(vascular endothelial growth factor,VEGF)和血小板源性生长因子(platelet-derived endothelial cell growth factor PD-ECG/TP)的表达,从肿瘤新生血管的形成方面来探讨ECCC的预后相关因素.方法 应用免疫组化法检测24例ECCC组织中VEGF、TP的表达,根据VEGF表达情况分成高表达组和低表达组,分析两组患者的生存差异.结果 在ECCC组织中,VEGF/TP均有较高的表达,两组患者的生存差异有统计学意义.结论 低表达组患者的生存时间长于高表达组.
目的 研究子宮內膜透明細胞癌ECCC(uterine endometrial clear cell carcinoma,ECCC)組織中血管內皮生長因子(vascular endothelial growth factor,VEGF)和血小闆源性生長因子(platelet-derived endothelial cell growth factor PD-ECG/TP)的錶達,從腫瘤新生血管的形成方麵來探討ECCC的預後相關因素.方法 應用免疫組化法檢測24例ECCC組織中VEGF、TP的錶達,根據VEGF錶達情況分成高錶達組和低錶達組,分析兩組患者的生存差異.結果 在ECCC組織中,VEGF/TP均有較高的錶達,兩組患者的生存差異有統計學意義.結論 低錶達組患者的生存時間長于高錶達組.
목적 연구자궁내막투명세포암ECCC(uterine endometrial clear cell carcinoma,ECCC)조직중혈관내피생장인자(vascular endothelial growth factor,VEGF)화혈소판원성생장인자(platelet-derived endothelial cell growth factor PD-ECG/TP)적표체,종종류신생혈관적형성방면래탐토ECCC적예후상관인소.방법 응용면역조화법검측24례ECCC조직중VEGF、TP적표체,근거VEGF표체정황분성고표체조화저표체조,분석량조환자적생존차이.결과 재ECCC조직중,VEGF/TP균유교고적표체,량조환자적생존차이유통계학의의.결론 저표체조환자적생존시간장우고표체조.
Objective To determine and analyze the relationship between VEGF/TP expression and ECCC patients'survival time.Mcthods 24 cases of ECCC were analyzed by immunohistechemistry.We separated the patients into high and Low expressions of VEGF group Results low or high expressions of VEGF and TP has a significant influential difference for the patients'survival time.Conclusion There is a close relationship between VEGF expression and prognosis of ECCC
