今日药学
今日藥學
금일약학
PHARMACY TODAY
2009年
7期
48-49
,共2页
肝素钠%离子色谱%草酸根
肝素鈉%離子色譜%草痠根
간소납%리자색보%초산근
heparin sodium%ion-chromatography%oxalic ion
目的 加强肝素钠的质量控制,建立草酸根检测方法.方法 采用离子色谱法对肝素钠中草酸根离子进行测定,并进行方法学验证.结果 线性相关系数r=0.9998,加样回收率为95.2%～99.7%,检测40批肝素钠原料发现部分草酸根离子含量较高.结论 本方法操作简单,结果准确,灵敏度高,可对肝素钠进行更进一步的质量控制.
目的 加彊肝素鈉的質量控製,建立草痠根檢測方法.方法 採用離子色譜法對肝素鈉中草痠根離子進行測定,併進行方法學驗證.結果 線性相關繫數r=0.9998,加樣迴收率為95.2%～99.7%,檢測40批肝素鈉原料髮現部分草痠根離子含量較高.結論 本方法操作簡單,結果準確,靈敏度高,可對肝素鈉進行更進一步的質量控製.
목적 가강간소납적질량공제,건립초산근검측방법.방법 채용리자색보법대간소납중초산근리자진행측정,병진행방법학험증.결과 선성상관계수r=0.9998,가양회수솔위95.2%～99.7%,검측40비간소납원료발현부분초산근리자함량교고.결론 본방법조작간단,결과준학,령민도고,가대간소납진행경진일보적질량공제.
Objective To establish a method to determine oxalic ion in heparin sodium, and to improve its quality control. Methods The oxalic ion in heparin sodium was determined by ion-chromatography, Results The linear coefficientcorrelation was 0.9998, and the recovery rate was 95.2%～99.7%. A total of 40 hatches of heparin sodium were tested. The content of oxalic ion in some of those batches was relatively high. Conclusion The method is simple and accurate.
