CAJ | 학술논문

目的:对剖宫产围手术期应用抗生素预防术后感染的优选抗生素进行探讨.方法:将符合纳入标准的产妇673例随机分为3组:氨苄西林组232例,头孢唑啉钠组223例,头孢曲松钠组218例.氨苄西林组与头孢唑啉钠组于术前半小时、术后立即及术后6小时静脉用药,头孢曲松钠组于术前半小时、术后6小时静脉用药,并评价术后预防感染的效果.结果:3组间的发热率、血象异常升高率差异无统计学意义(P>0.05);氨苄西林组腹部切口感染率分别与头孢唑啉钠组、头孢曲松钠组比较,差异有统计学意义(P<0.05),头孢唑啉钠组腹部切口感染率与头孢曲松组比较,差异无统计学意义(P>0.05);3组患者术后均未出现宫腔感染、盆腹腔感染及泌尿系统感染.结论:围手术期应用氨苄西林预防剖宫产术后感染,具有预防感染效果肯定、安全及价廉等优点,是具有广泛临床推广价值的用药方案.
목적:대부궁산위수술기응용항생소예방술후감염적우선항생소진행탐토.방법:장부합납입표준적산부673례수궤분위3조:안변서림조232례,두포서람납조223례,두포곡송납조218례.안변서림조여두포서람납조우술전반소시、술후립즉급술후6소시정맥용약,두포곡송납조우술전반소시、술후6소시정맥용약,병평개술후예방감염적효과.결과:3조간적발열솔、혈상이상승고솔차이무통계학의의(P>0.05);안변서림조복부절구감염솔분별여두포서람납조、두포곡송납조비교,차이유통계학의의(P<0.05),두포서람납조복부절구감염솔여두포곡송조비교,차이무통계학의의(P>0.05);3조환자술후균미출현궁강감염、분복강감염급비뇨계통감염.결론:위수술기응용안변서림예방부궁산술후감염,구유예방감염효과긍정、안전급개렴등우점,시구유엄범림상추엄개치적용약방안.
Objective:To investigate the optimal antibiotics to prevent postoperative infection during perioperative period in cesarean section. Methods: A total of 673 patients enrolled in the study were divided into 3 groups randomly, Group A (Ampicillin, n=232), Group B (Cefazolin, n=223) and Group C (Ceftriaxone, n =218). The antibiotics were injected by intravenous drop infusion 30 minutes before operation, immediately after operation and 6 hours after operation in group A and B, but in group C without the time point immediately after operation. The effects on prevention of infection by the antibiotics were evaluated. Results: There was no significant difference among these 3 groups in the incidence of fever and hemogram abnormality (P> 0.05). The rate of abdominal incision postoperative infections was significantly lower in Group A compared with Group B and Group C ( P < 0. 05), while there was no significant difference between Group B and Group C( P>0.05). There was no intrauterine infection, abdominopelvic cavity or urinary system infection among these three groups. Conclusions:Using Ampicillin to prevent postoperative infection during perioperative period is a widespread, promotional schedule which has the advantages of good effects, safety and cheap.