九江学院学报：自然科学版
九江學院學報：自然科學版
구강학원학보：자연과학판
Journal of Jiujiang University
2011年
4期
44-46
,共3页
扁平疣%卡介菌多糖核酸%阿维A%维A酸乳膏%治疗
扁平疣%卡介菌多糖覈痠%阿維A%維A痠乳膏%治療
편평우%잡개균다당핵산%아유A%유A산유고%치료
cream%Treatment verruca plana%BCG polysaccharide and nucleic acid%Acitretin%tretinoin
目的观察卡介菌多糖核酸联合阿维A治疗扁平疣的临床疗效。方法将96例扁平疣患者随机分为3组，A组予以卡介菌多糖核酸注射液2ml，肌肉注射，隔日1次，共18次；阿维A胶囊20mg，随牛奶或主餐口服，1次／d；B组予以卡介菌多糖核酸注射液2mL，肌肉注射，隔日1次，共18次；C组予以阿维A胶囊20mg，随牛奶或主餐口服，1次／天；3组均同时外用0．1％维A酸乳膏，连续36d。结果A组有效率87．50％，B组有效率84．38％，C组有效率68．75％。A组与B组的有效率比较差异无统计学意义（x2=0．129，P〉0．05），但治愈率比较差异有统计学意义（X2=5．063，P〈0．05）；A组与C组的有效率比较有显著性差异（x2=4．48，P〈0．05）；B组与c组的有效率比较差异无统计学意义（X2=2．755，P〉0．05）。结论卡介菌多糖核酸联合阿维A治疗扁平疣较两药分别单用为好，疗效肯定，副作用小，复发率低。
目的觀察卡介菌多糖覈痠聯閤阿維A治療扁平疣的臨床療效。方法將96例扁平疣患者隨機分為3組，A組予以卡介菌多糖覈痠註射液2ml，肌肉註射，隔日1次，共18次；阿維A膠囊20mg，隨牛奶或主餐口服，1次／d；B組予以卡介菌多糖覈痠註射液2mL，肌肉註射，隔日1次，共18次；C組予以阿維A膠囊20mg，隨牛奶或主餐口服，1次／天；3組均同時外用0．1％維A痠乳膏，連續36d。結果A組有效率87．50％，B組有效率84．38％，C組有效率68．75％。A組與B組的有效率比較差異無統計學意義（x2=0．129，P〉0．05），但治愈率比較差異有統計學意義（X2=5．063，P〈0．05）；A組與C組的有效率比較有顯著性差異（x2=4．48，P〈0．05）；B組與c組的有效率比較差異無統計學意義（X2=2．755，P〉0．05）。結論卡介菌多糖覈痠聯閤阿維A治療扁平疣較兩藥分彆單用為好，療效肯定，副作用小，複髮率低。
목적관찰잡개균다당핵산연합아유A치료편평우적림상료효。방법장96례편평우환자수궤분위3조，A조여이잡개균다당핵산주사액2ml，기육주사，격일1차，공18차；아유A효낭20mg，수우내혹주찬구복，1차／d；B조여이잡개균다당핵산주사액2mL，기육주사，격일1차，공18차；C조여이아유A효낭20mg，수우내혹주찬구복，1차／천；3조균동시외용0．1％유A산유고，련속36d。결과A조유효솔87．50％，B조유효솔84．38％，C조유효솔68．75％。A조여B조적유효솔비교차이무통계학의의（x2=0．129，P〉0．05），단치유솔비교차이유통계학의의（X2=5．063，P〈0．05）；A조여C조적유효솔비교유현저성차이（x2=4．48，P〈0．05）；B조여c조적유효솔비교차이무통계학의의（X2=2．755，P〉0．05）。결론잡개균다당핵산연합아유A치료편평우교량약분별단용위호，료효긍정，부작용소，복발솔저。
Objective： To observe the clinical effects of BCG polysaccharide and nucleic acid injection and acitretin in teeatment of verruca plana. Methods ： 96 cases of verruca plana patient were stochastically divided into 3 groups , Having group A given BCG polysaccharide and nucleic acid injection 2ml, intramuscular, every other day one time, altogether 18 times; acitretin capsule 20mg, along with milk or main meal oral administration, 1 /d; group B given BCG polysaccharide and nucleic acid injection 2ml, intramuscular, every other day one time, altogether 18 times; group C given acitretin capsule 20rag, along with milk or main meal oral administration, 1/d. At same time, 3 group patients were given external use 0. 1% tretinoin cream, lasted 36 days. Results： The effectiveness of Group A was 87.50%, the effectiveness of Group B 84.38%, the effectiveness of Group C 68. 75%. A group compares the non -significance difference with B group of effectiveness （x2 =0. 129, p 〉0. 05 ）, but the cure rate comparison has the significance difference （x2 = 5. 063, p 〈 O. 05 ） ; A group has the significance difference with C group of effectiveness comparison （x2 = 4. 48, p 〈 0. 05 ） ; B group compares the non - significance difference with C group of effectiveness （ x2 = 2. 755, p 〉 O. 05 ）. Conclusions： BCG polysaccharide and nucleic acid injection and acitretin to treat the verruca plana compared to two medicine distinction alone application for good, the curative effect affirmed, the side effect is small, the recurrence rate is low.
