CAJ | 학술논문

乳凝集素是一种黏附在乳汁脂肪球膜表面的镶嵌型外周蛋白,在机体其他体液中也有表达,存在于多物种内,发挥多种功能:增进凋亡淋巴细胞及其他凋亡细胞的吞噬清除,促进肠黏膜的修复,增加树突状细胞外泌小体功能,促进乳腺分支的形态发生,促血管形成,调节精子与卵细胞外围的黏附等.该文主要综述乳凝集素的结构功能及其在治疗方面的应用前景.
유응집소시일충점부재유즙지방구막표면적양감형외주단백,재궤체기타체액중야유표체,존재우다물충내,발휘다충공능:증진조망림파세포급기타조망세포적탄서청제,촉진장점막적수복,증가수돌상세포외비소체공능,촉진유선분지적형태발생,촉혈관형성,조절정자여란세포외위적점부등.해문주요종술유응집소적결구공능급기재치료방면적응용전경.
Lactadherin is an important membrance-associated glycoprotein that detected on the surface of human milk fat globule. It has been independently identified in many species and now known to participate in a wide variety of cellular interactions, including phagocaryosis of apoptotic lymphcytes and other apoptotic cells, repairing of intestinal mucosa, facilitateing exosome-function in dendritic cells, mammary gland branching morphogenesis, angiogenesis,adhesion between sperm and the egg coat, etc. This article explores the various functions of lactadherin, as well as its therapeutic potential.