CAJ | 학술논문

目的：探讨动态血压监测(ABPM)在评价高血压靶器官损害中的预测价值。方法：对 120例原发性高血压(EH)患者(女42例，男78例)的24 h ABPM和偶测血压(CBP)与EH所致靶器官损害(心房颤动、室性心律失常、充血性心力衰竭、脑血管意外)的相关性进行比较。结果：24 h动态平均SBP和上述各项事件有明显的相关性，相关系数分别为0．300 1，0．3114，0．392 1，0．422 2，P<0．01；24 h动态平均DBP亦和上述各项事件有相关性，相关系数依次为0．299 8，0．309 5、0．243 0，0．300 5，P<0．01；CBP与EH所致靶器官损害无相关性。脑血管意外的发生与夜间平均SBP和DBP有更明显的相关性，相关系数分别为0．600 5，0．456 8，P<0．001。研究还发现动态血压中有"杓"型变化者比无"杓"型变化者的EH心脑血管并发症发病率明显降低。血压负荷>25％是心脑血管病发生的危险信号之一。结论：了解EH患者的24 h血压变化对预测EH并发症的发生和指导合理治疗有重要意义。注重夜间血压的降低是减少脑血管病发生的一有效措施。
목적：탐토동태혈압감측(ABPM)재평개고혈압파기관손해중적예측개치。방법：대 120례원발성고혈압(EH)환자(녀42례，남78례)적24 h ABPM화우측혈압(CBP)여EH소치파기관손해(심방전동、실성심률실상、충혈성심력쇠갈、뇌혈관의외)적상관성진행비교。결과：24 h동태평균SBP화상술각항사건유명현적상관성，상관계수분별위0．300 1，0．3114，0．392 1，0．422 2，P<0．01；24 h동태평균DBP역화상술각항사건유상관성，상관계수의차위0．299 8，0．309 5、0．243 0，0．300 5，P<0．01；CBP여EH소치파기관손해무상관성。뇌혈관의외적발생여야간평균SBP화DBP유경명현적상관성，상관계수분별위0．600 5，0．456 8，P<0．001。연구환발현동태혈압중유"표"형변화자비무"표"형변화자적EH심뇌혈관병발증발병솔명현강저。혈압부하>25％시심뇌혈관병발생적위험신호지일。결론：료해EH환자적24 h혈압변화대예측EH병발증적발생화지도합리치료유중요의의。주중야간혈압적강저시감소뇌혈관병발생적일유효조시。
Objective: To study the value of ABPM in predicting target organ damage caused by hypertension. Method:We studied the relationship between 24 h ambulatory blood pressure monitoring (24 h ABPM), casual blood pressure (CBP) and target organ damage (atrial fibrillation, ventricular arrhythemia, congestive heart failure,cerebral vascular accident) caused by hypertension in 120 cases of hypertension (42 femals, 78 males). Result: 24 h ambulatory mean BP had clear relevance to the events mentioned above. The relevant factors were 0. 300 1,0. 311 4,0. 392 1,0. 422 2 respectively (P ＜0.01). 24 h mean.dBP was also relevant to them, the relevance factors were 0. 299 8, 0. 309 5,0. 243 0,0. 300 5 respectively (P ＜ 0.01 ), CBP was not relevant to the target organ damage caused by hypertension. Tbe occurrence of cerelbal vascular diseases was clearly relevant to nocturnal mean SBP and dBP,the relevant factors were 0. 600 5,0. 456 8 respectively ( P ＜0. 001). In the study, we found that the occurence rate of cardiocerebral vascular complications was much lower among HT patients who had a ABPM with a "dipper" type than patients who did not. BP load＞25% was one signal for occurrence of cardiocerebral vascular diseases. Conclusion: ABPM may help us to predict the incidence of complications related to HT and provide optimal treatment. Lowering noctunal BP is an effective way of reducing the incidence of cerehrovascular complication